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NCT06824207: Vakzimeter RSV

Repeated Cross Sectional Surveillance Study To Determine the Respiratory Syncytial Virus (RSV) Immunization Rates in German Infants

Active, enrolled Last updated 5 June 2025
What this trial tests

trial in Respiratory Syncytial Virus Immunization in 2,400 participants. Participants enrolled and being followed up; not accepting new ones.

Timeline
13 January 2025
Primary endpoint
30 May 2026
30 May 2026

Quick facts

Lead sponsorSanofi Pasteur, a Sanofi Company
StatusActive, enrolled
Study typeOBSERVATIONAL
Enrollment2,400
Start date13 January 2025
Primary completion30 May 2026
Estimated completion30 May 2026
Sites1 location across Germany

Conditions studied

Sponsor

Sanofi Pasteur, a Sanofi Company — full company profile →

Who can join

18 and older, any sex, with Respiratory Syncytial Virus Immunization. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

In June 2024, the German Standing Committee on Vaccination (STIKO) recommended the universal immunization of infants with nirsevimab during their first RSV season. Nirsevimab is a long-acting monoclonal antibody designed to provide passive immunity against RSV, significantly reducing the risk of severe RSV disease in infants. This recommendation marks the 2024/25 season as the first in which nirsevimab is broadly implemented for all infants in Germany. Despite the introduction of this new prevention measure, there is currently no timely monitoring system for immunization rates. Understanding the uptake and coverage of nirsevimab is crucial for evaluating its impact on public health and guiding future vaccination strategies. Therefore, this study aims to monitor the national immunization rates of nirsevimab in children under one year of age during the initial seasons of its widespread use. The primary objective of this study is to determine the Nirsevimab immunization rate in eligible infants in their first RSV-season in Germany. The study will focus on: 1. Assessing the immunization rates among eligible infants (according to STIKO recommendation) in their first RSV-season in Germany (i.e. across all geographies) 2. Assessing the immunisation rates among the "catch-up cohort", i.e. all infants born between April and September. For these infants, the STIKO recommends immunization with nirsevimab in early autumn. 3. Assessing the immunization rate among the "in-season cohort", i.e. all infants born during the RSV season between October and March. For these newborns, the STIKO recommends immunization with Nirsevimab shortly after birth, preferably during the second "well-baby visit" at the age of 3-10 days of life.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other Sanofi Pasteur, a Sanofi Company trials

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Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06824207.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing