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NCT06823349: SSSA
Comparative Analysis of Analgesic Efficacy: by Single Shot Intrathecal Analgesia (SSSA) in Normal Labor
Phase 4 trial testing Dexmedetomidine in Vaginal Delivery in 90 participants. Currently enrolling.
30 June 2025
Quick facts
| Lead sponsor | Jehan George Sadek |
|---|---|
| Phase | Phase 4 |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 90 |
| Start date | 1 February 2025 |
| Primary completion | 30 June 2025 |
| Estimated completion | 31 July 2025 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Dexmedetomidine (dexmedetomidine) — full drug profile →
- fentanyl (fentanyl) — full drug profile →
- Saline 0.9% — full drug profile →
Conditions studied
- Vaginal Delivery — all drugs for Vaginal Delivery →
- Normal Labor — all drugs for Normal Labor →
Sponsor
Jehan George Sadek
Who can join
Eligibility, female only, with Vaginal Delivery or Normal Labor. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
the goal of this randomized control trial is to compare the effect of adding fentanyl v.s dexmedetomidine to bupivacaine in single shot spinal analgesia in achievement of analgesia by decreasing visual analogue scale, onset and increasing duration of analgesia in normal labor.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Single-Shot Intrathecal Bupivacaine With Fentanyl vs. Dexmedetomidine for Labor Analgesia: A Randomized Controlled Trial.
Eldemrdash AM, Elsawy TTD, Zaher ZZ, Younan JS, et al · · 2026 · PMID 42063584 · DOI 10.1155/anrp/6685169
Verify or expand the search:
- PubMed search for NCT06823349
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Dexmedetomidine
Trials testing the same drug.
- NCT06824077 — Reducing Days DELirious With DEXmedetomidine as Part of an Intensive Care Unit Sleep Promotion Bundle · EARLY_PHASE1 · not yet recruiting
- NCT07398066 — DEXmedetomidine for Postoperative Analgesia and Delirium Prevention After NEUROsurgery (DEX-NEURO Trial) · NA · not yet recruiting
- NCT07377981 — An Exploratory Study of the Efficacy and Safety of Esketamine and Dexmedetomidine in Non-Intubated ICU Patients With Hyp · Phase 4 · not yet recruiting
- NCT07306702 — Dexmedetomidine-Enhanced PCIA After Lobectomy in Nicotine-Dependent Patients · Phase 4 · withdrawn
- NCT07482540 — Role of Dexmedatomidine Drug in Prevention of Atrial Fibrillations Post Mitral Valve Surgery · NA · not yet recruiting
Other recruiting trials for Vaginal Delivery
Currently open trials in the same condition.
- NCT07212361 — Infant Microbiota Restoration With Maternal Microbes · NA · recruiting
- NCT06568289 — Lignocaine vs Bupivacaine Infiltration for Postpartum Perineal Pain After Vaginal Delivery With Episiotomy in Primigravi · NA · recruiting
- NCT03973281 — EASE: The Materna Prep Pivotal Study · NA · active not recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06823349 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Jehan George Sadek
- Last refreshed: 31 July 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06823349.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing