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NCT06822699
The Influence of Leg Elevation on Noradrenaline Requirements During Cesarean Delivery
NA trial testing Leg elevation in Spinal Hypotension in 80 participants. Completed in 8 May 2025.
8 May 2025
Quick facts
| Lead sponsor | Cairo University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | prevention |
| Enrollment | 80 |
| Start date | 14 March 2025 |
| Primary completion | 8 May 2025 |
| Estimated completion | 8 May 2025 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Leg elevation
Conditions studied
- Spinal Hypotension — all drugs for Spinal Hypotension →
- Hypoperfusion — all drugs for Hypoperfusion →
Sponsor
Cairo University
Who can join
Adults 20 to 40, female only, with Spinal Hypotension or Hypoperfusion. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Spinal anesthesia is a widely chosen technique in obstetric theaters due to several advantages, however sympathetic block results in hypotension that carry several consequences on maternal and fetal health, thus early prediction and management takes high priority. in this regards recent recommendations suggest the use of prophylactic vasopressors like noradrenaline, researchers of this study aimed to explore the impact of leg elevation on prophylactic noradrenaline dose
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
The influence of thirty-degree leg elevation on noradrenaline requirements administered as a prophylactic variable infusion during cesarean delivery, an open-label randomized controlled trial.
Helmy MA, Naguib NN, Helmy KA, Milad LM. · · 2025 · cited 3× · PMID 41152963 · DOI 10.1186/s44158-025-00290-7
Verify or expand the search:
- PubMed search for NCT06822699
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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Related trials
Other trials of Leg elevation
Trials testing the same drug.
- NCT07534891 — The Effect of Compression Stockings and Leg Elevation on Hemodynamic Stability in Elective Cesarean Sections Under Spina · NA · completed
Other Cairo University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06822699 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Cairo University
- Last refreshed: 13 May 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06822699.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing