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NCT06808399: ASYMRUN
The Magnitude of Inter-limb Asymmetry and Its Assocation with Inter-limb Asymmetry in Distance Runners and Non-runners
trial in Healthy in 72 participants. Currently enrolling.
1 June 2025
Quick facts
| Lead sponsor | Vrije Universiteit Brussel |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 72 |
| Start date | 1 January 2023 |
| Primary completion | 1 June 2025 |
| Estimated completion | 1 June 2025 |
| Sites | 1 location across Belgium |
Conditions studied
- Healthy — all drugs for Healthy →
Sponsor
Vrije Universiteit Brussel — full company profile →
Who can join
Adults 20 to 50, any sex, with Healthy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Distance running is one of the most popular and most accessible ways to engage in physical activity. Although distance running offers numerous health-related benefits and protects against noncommunicable diseases (e.g., type 2 diabetic, obesity, hypertension), research has indicated a high prevalence of running-related injuries with a more pronounced incidence among novice runners (i.e., 17.8 injuries per 1000h) compared to their highly trained peers (i.e., 7.2 injuries per 1000h). Interlimb asymmetry has previously been related to higher injury risk as well as to impaired sports performances. Nevertheless, to date, research on the degree and evolution of functional asymmetry (e.g., unequal strength between limbs) in distance runners is scarce and the role of functional asymmetries in running performance and running-related injuries remains unclear. Moreover, and despite the great number of unilateral tests available in the literature, there currently exists no reliable and run-specific field-based test battery to examine the degree of lower limb asymmetry in distance runners. Therefore, this study aims to assess the test-retest, intra- and inter-rater reliability of a newly created running-specific field-based test battery to assess the presence and degree of functional lower limb asymmetry among novice, moderatly and highly trained distance runners as well as a control group of non-athletes. The second objective is to assess the association between inter-limb asymmetry and running performance.
Publications & conference data
4 peer-reviewed publications reference this trial (live from Europe PMC):
-
Test-retest and inter-rater reliability of a field-based test battery to assess lower limb isometric strength and inter-limb asymmetry in healthy adult endurance runners of various training levels
D’HONDT J, CHAPELLE L, BISHOP C, AERENHOUTS D, et al · · 2026 · DOI 10.21203/rs.3.rs-9354122/v1 -
Inter-limb range of motion and jumping asymmetry linked to running performance in healthy adult recreational endurance runners: A cross-sectional study
D’Hondt J, Bishop C, D’Hondt E, Chapelle L, et al · · 2026 · DOI 10.21203/rs.3.rs-9012614/v1 -
Variations in morphological lower inter-limb asymmetry by sex and training level, and its link to performance in recreational runners: A cross-sectional study
D’Hondt J, D’Hondt E, Aerenhouts D, Pauw K, et al · · 2026 · DOI 10.21203/rs.3.rs-9008534/v1 -
Consistency Between Lower Limb Preference and Dominance in Healthy Adult Distance Runners: Exploring its Variability Across Tasks and Time
D’Hondt J, Bishop C, Chapelle L, De Pauw K, et al · · 2025 · DOI 10.21203/rs.3.rs-8147618/v1
Verify or expand the search:
- PubMed search for NCT06808399
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06808399 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Vrije Universiteit Brussel
- Last refreshed: 5 February 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06808399.
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