NCT06808386: ETFRPPRRCT

Effects of Training Frequency on Patellofemoral Pain Rehabilitation.

ENROLLING BY INVITATION NA Last updated 5 February 2025

What this trial tests

NA trial testing Strengthening 2 times per week in Anterior Knee Pain in 84 participants. Enrolling by invitation.

Timeline

24 February 2025

Primary endpoint
30 November 2026

21 December 2026

Quick facts

Lead sponsor	University of Nove de Julho
Phase	NA
Status	ENROLLING BY INVITATION
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	84
Start date	24 February 2025
Primary completion	30 November 2026
Estimated completion	21 December 2026
Sites	1 location across Brazil

Drugs / interventions tested

• Strengthening 2 times per week
• Strengthening 3 times per week

Conditions studied

• Anterior Knee Pain — all drugs for Anterior Knee Pain →

Sponsor

University of Nove de Julho

Who can join

Adults 18 to 40, any sex, with Anterior Knee Pain. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This clinical trial aims to determine the optimal frequency of exercise therapy for improving pain, function, and quality of life in participants with patellofemoral pain. The main questions it aims to answer are:

Does exercising twice a week provide the same benefits as exercising three times a week for individuals with patellofemoral pain? What are the optimal dosage, volume, and weekly exercise frequency for treating patellofemoral pain?

The investigators will compare two groups of participants: one group of participants receiving exercise therapy twice a week and another group receiving exercise therapy three times a week. Both groups will follow the same exercise protocol targeting the muscles of the hip and knee joints.

Participants:

84 volunteers (both male and female) with patellofemoral pain Physically active individuals aged between 18 and 40 years

Interventions:

Participants will be randomly assigned to one of two groups Both groups will perform the same exercises for hip and knee muscle strengthening Group A will exercise three times per week Group B will exercise two times per week The intervention will last for six consecutive weeks

Assessments: Participants will be evaluated at the following time points:

Before the intervention After the 4th and 6th week of intervention 6 months and 1 year after the end of the intervention

The primary Outcome Measure will be pain intensity.

Secondary Outcome Measure:

Anterior knee pain during daily activities Kinesiophobia Pain-related self-efficacy Chronic pain-related self-efficacy Catastrophizing Muscle strength 3D Movement analysis

Data Analysis:

The investigators will use an intention-to-treat analysis, which means that all participants will be included in the study, regardless of whether they completed the treatment as planned.

Appropriate statistical tests will be used to compare differences within and between the two groups, considering the time points and group factors.

A 5% significance level will be adopted, which means there is a 5% chance that the results are due to random variation rather than the treatment effect.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.