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NCT06803563

Physical Exercise, Motor Activity on Sleep Disorders in Post-Mastectomy Pain Syndrome

Completed Last updated 31 January 2025
What this trial tests

trial in Chronic Pain Syndrome in 180 participants. Completed in 30 November 2024.

Timeline
17 July 2024
Primary endpoint
30 November 2024
30 November 2024

Quick facts

Lead sponsorGioacchino Calapai
StatusCompleted
Study typeOBSERVATIONAL
Enrollment180
Start date17 July 2024
Primary completion30 November 2024
Estimated completion30 November 2024
Sites1 location across Italy

Conditions studied

Sponsor

Gioacchino Calapai

Who can join

Adults 18 to 75, female only, with Chronic Pain Syndrome. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Pain is an unpleasant sensation common to all those who undergo surgery. Several studies indicate that 40-60% of patients experience the post-operative experience and can be caused by both internal and external stimuli. Chronic post mastectomy pain is a condition characterized by pain in the anterior chest, armpit, and/or upper arm, usually ipsilateral to surgery, which begins after mastectomy or quadrantectomy and persists for longer three months after surgery. It can become chronic in a broad spectrum of conditions. Psychosocial factors such as anxiety and sleep disturbance are being revealed as crucial contributors to individual differences in pain processing and outcomes. Some researchers have reported the associations between the development of persistent pain, sleep disorders and reduced physical activity. Taken together, these symptoms may lead to disability and worsened quality of life. Due to its benefits, the American Cancer Society recommends to begin as soon as possible from the diagnosis of cancer, physical activity. Aim of this prospective observational study is to evaluate the effects of motor and/or sports activity on the intensity of chronic pain and in symptoms of sleep disorders, caused by post-mastectomy chronic pain. of life of women underwent mastectomy

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Post-mastectomy pain syndrome and sleep disorders: effects of physical activity.
    Calapai M, Puzzo L, Bova G, Vecchio DA, et al · · 2025 · PMID 41357821 · DOI 10.3389/fspor.2025.1579635

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