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A Phase 1 Study of Vaccination With Dendritic Cell (DC)/Multiple Myeloma (MM) Fusions in Combination With Elranatamab in Relapsed or Refractory Multiple Myeloma

NCT06799026 PHASE1 RECRUITING

This research is being done to determine if the combination of the Dendritic Cell (DC)/ Multiple Myeloma (MM) fusion vaccine with elranatamab is safe and effective in treating Relapsed or Refractory Multiple Myeloma (MM). The names of the study drugs and vaccine involved in this study are: * DC/MM fusion vaccine (a personalized cancer vaccine in which harvested participant tumor cells are fused with harvested participant dendritic blood cells) * Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) (a type of growth factor) * Elranatamab (a type of T-cell engager antibody)

Details

Lead sponsorDavid Avigan
PhasePHASE1
StatusRECRUITING
Enrolment25
Start dateFri Jan 31 2025 00:00:00 GMT+0000 (Coordinated Universal Time)
CompletionSun Sep 01 2030 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

Interventions

Countries

United States