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A Phase 1 Study of Vaccination With Dendritic Cell (DC)/Multiple Myeloma (MM) Fusions in Combination With Elranatamab in Relapsed or Refractory Multiple Myeloma
This research is being done to determine if the combination of the Dendritic Cell (DC)/ Multiple Myeloma (MM) fusion vaccine with elranatamab is safe and effective in treating Relapsed or Refractory Multiple Myeloma (MM). The names of the study drugs and vaccine involved in this study are: * DC/MM fusion vaccine (a personalized cancer vaccine in which harvested participant tumor cells are fused with harvested participant dendritic blood cells) * Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) (a type of growth factor) * Elranatamab (a type of T-cell engager antibody)
Details
| Lead sponsor | David Avigan |
|---|---|
| Phase | PHASE1 |
| Status | RECRUITING |
| Enrolment | 25 |
| Start date | Fri Jan 31 2025 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Sun Sep 01 2030 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Multiple Myeloma
- Relapse Multiple Myeloma
- Refractory Multiple Myeloma
Interventions
- Elranatamab
- GM-CSF
- DC/MM Fusion Vaccine
Countries
United States