NCT06791239

Comparison of Thoracic Squeeze and Manual Diaphragmatic Release Technique in COPD Patients

Completed NA Last updated 22 August 2025

What this trial tests

NA trial testing Thoracic squeeze technique in COPD (Chronic Obstructive Pulmonary Disease) in 36 participants. Completed in 30 June 2025.

Timeline

1 February 2025

Primary endpoint
30 May 2025

30 June 2025

Quick facts

Lead sponsor	Riphah International University
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	other
Enrollment	36
Start date	1 February 2025
Primary completion	30 May 2025
Estimated completion	30 June 2025
Sites	1 location across Pakistan

Drugs / interventions tested

• Thoracic squeeze technique
• Manual diaphragmatic release technique

Conditions studied

• COPD (Chronic Obstructive Pulmonary Disease) — all drugs for COPD (Chronic Obstructive Pulmonary Disease) →

Sponsor

Riphah International University

Who can join

Adults 40 to 60, female only, with COPD (Chronic Obstructive Pulmonary Disease). Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of this randomized control trial is to evaluate and compare the efficacy of two physiotherapy techniques-Thoracic Squeeze Technique (TST) and Manual Diaphragmatic Release Technique (MDRT)-on improving respiratory parameters, functional capacity, and quality of life in patients with mild to moderate Chronic Obstructive Pulmonary Disease (COPD).

Objectives:

* Assess the impact of TST and MDRT on respiratory parameters (FEV1, FVC, FEV1/FVC ratio, and chest expansion).
* Compare the functional capacity outcomes of the two techniques using the 6-Minute Walk Test (6MWT).
* Evaluate the effects of TST and MDRT on patient wellbeing and daily life through the COPD Assessment Test (CAT).

Study Design:

The study involves 34 participants, divided into two groups (n=17 each) via sealed envelope randomization. Both groups will receive their respective interventions (TST or MDRT) alongside a standardized pulmonary rehabilitation protocol (pursed-lip breathing, diaphragmatic breathing, active cycle of breathing, and endurance exercises). The intervention will be conducted three times per week for three weeks.

Outcome Measures:

Primary outcomes include respiratory parameters assessed through spirometry and chest expansion using a measuring tape. Secondary outcomes include functional capacity (6MWT) and patient wellbeing (CAT scores). Baseline and post-intervention measures will be analyzed using SPSS, employing Mixed ANOVA to determine interaction effects.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.