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NCT06789549
Epinephrine Nasal Drops for Epistaxis During Nasal Intubation
Phase 2 trial testing epinephrine nasal drops in Oral Surgery in 40 participants. Completed in 1 April 2024.
20 March 2024
Quick facts
| Lead sponsor | Universitas Padjadjaran |
|---|---|
| Phase | Phase 2 |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | prevention |
| Enrollment | 40 |
| Start date | 1 January 2024 |
| Primary completion | 20 March 2024 |
| Estimated completion | 1 April 2024 |
| Sites | 1 location across Indonesia |
Drugs / interventions tested
- epinephrine nasal drops — full drug profile →
- oxymetazoline nasal drops
Conditions studied
- Oral Surgery — all drugs for Oral Surgery →
Sponsor
Universitas Padjadjaran — full company profile →
Who can join
Adults 18 to 50, any sex, with Oral Surgery. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Epistaxis is the most common complication of nasotracheal intubation. Incidence of epistaxis during nasotracheal intubation ranges from 22% to 80%. Epistaxis during nasotracheal intubation can lead to several complications such as nasal discomfort, airway obstruction, and blood aspiration. The most commonly used and available topical vasoconstrictor in drop form is oxymetazoline. However, oxymetazoline may not always be available in some hospitals, so epinephrine can be used as an alternative nasal decongestant to reduce the incidence of epistaxis during nasotracheal intubation.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06789549
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Oral Surgery
Currently open trials in the same condition.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06789549 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Universitas Padjadjaran
- Last refreshed: 23 January 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06789549.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing