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NCT06788769

Study of Clostridioides Difficile in Infants

Recruiting now Last updated 23 January 2025
What this trial tests

trial in Clostridioides Difficile Infection in 300 participants. Currently enrolling.

Timeline
1 July 2024
Primary endpoint
30 August 2026
30 December 2026

Quick facts

Lead sponsorWestlake University
StatusRecruiting now
Study typeOBSERVATIONAL
Enrollment300
Start date1 July 2024
Primary completion30 August 2026
Estimated completion30 December 2026
Sites1 location across China

Conditions studied

Sponsor

Westlake University

Who can join

Adults 1 Day to 2, any sex, with Clostridioides Difficile Infection. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Clostridioides difficile infection (CDI) poses an increasing threat to infant and young child health, with detection rates rising annually. This retrospective study aims to explore the epidemiological characteristics, clinical manifestations, and potential biomarkers of CDI in children aged 0-2 years by examining three cohorts: (1) infants diagnosed with CDI, (2) asymptomatic carriers of C. difficile, and (3) healthy controls. Fecal samples from each group will undergo metagenomic sequencing and metabolomic profiling, coupled with questionnaire-based surveys for risk factor assessment. The findings are anticipated to identify key high-risk factors, elucidate the pathogenic mechanisms underlying infant CDI, and support the development of early diagnostic tools and preventive strategies.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other recruiting trials for Clostridioides Difficile Infection

Currently open trials in the same condition.

Other Westlake University trials

Trials by the same sponsor.

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Data sources for this page

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