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NCT06786780: ECCO
Establishment and Validation of Prediction Model of Simultaneous Chemoradiotherapy for Cervical Cancer Organoids
Phase 2 trial testing Drug: Cisplatin in Cervical Cancer Treated with Pelvic Radiotherapy in 50 participants. Enrolling by invitation.
1 June 2025
Quick facts
| Lead sponsor | Chongqing University Cancer Hospital |
|---|---|
| Phase | Phase 2 |
| Status | ENROLLING BY INVITATION |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 50 |
| Start date | 1 January 2023 |
| Primary completion | 1 June 2025 |
| Estimated completion | 1 June 2026 |
| Sites | 1 location across China |
Drugs / interventions tested
- Drug: Cisplatin
Conditions studied
- Cervical Cancer Treated with Pelvic Radiotherapy — all drugs for Cervical Cancer Treated with Pelvic Radiotherapy →
- Cervical Cancers — all drugs for Cervical Cancers →
Sponsor
Chongqing University Cancer Hospital
Who can join
18 and older, female only, with Cervical Cancer Treated with Pelvic Radiotherapy or Cervical Cancers. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This is a single-arm, single-center, open-label, Phase II study aimed at assessing the efficacy of organoids in predicting the response to radiotherapy and chemotherapy in cervical cancer
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Tumor Organoid and Microenvironment Cocultures: Implications for Basic and Translational Cancer Research.
Yang J, Cheng C, Luo W, He X, et al · · 2026 · PMID 41987851 · DOI 10.1002/mco2.70741 -
Recapitulating the tumour microenvironment: advancing personalised radiation therapy through organoid technology.
Lan Z, Liu J, Li L, Yang Y, et al · · 2026 · PMID 41761263 · DOI 10.1186/s13046-026-03655-0 -
Modeling Drug and Radiation Resistance with Patient-Derived Organoids: Recent Progress, Unmet Needs, and Future Directions for Lung Cancer.
Lee D, Kim Y, Kang DH, Chung C. · · 2025 · PMID 41440014 · DOI 10.3390/cells14241994
Verify or expand the search:
- PubMed search for NCT06786780
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06786780 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Chongqing University Cancer Hospital
- Last refreshed: 26 March 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06786780.
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