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NCT06785545

Urinary CA19-9 Level in the Differential Diagnosis of Neurogenic and Non-Neurogenic Lower Urinary Tract Dysfunction in Children

Status unknown NA Last updated 21 January 2025
What this trial tests

NA trial testing CA19-9 in Lower Urinary Track Symptoms in 100 participants. Status unknown.

Timeline
1 January 2024
Primary endpoint
12 November 2024
30 January 2025

Quick facts

Lead sponsorMarmara University
PhaseNA
StatusStatus unknown
Study typeINTERVENTIONAL
Allocationnon randomized
Designparallel
Maskingnone
Primary purposescreening
Enrollment100
Start date1 January 2024
Primary completion12 November 2024
Estimated completion30 January 2025
Sites1 location across Turkey (Türkiye)

Drugs / interventions tested

Conditions studied

Sponsor

Marmara University

Who can join

Adults 5 to 18, any sex, with Lower Urinary Track Symptoms. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

It has been shown in the literature that urinary CA19-9 levels are associated with the degree of hydronephrosis and the anteroposterior diameter of the renal pelvis. Additionally, this marker has been reported as a potential indicator of kidney damage related to obstructive uropathies. A study conducted in our clinic, which has yet to be published, investigated CA19-9 levels in children with hydronephrosis of different etiologies. It found a statistically significant difference in CA19-9 levels between children with neurogenic and non-neurogenic lower urinary tract (LUT) dysfunction (Evaluation of Spot Urine Carbohydrate Antigen 19-9, Sodium, Potassium, and Creatinine Levels as Biomarkers for Differential Diagnosis of Hydronephrosis and Detection of Kidney Damage in Children Aged 0-16: A Prospective Study, Kütükoğlu et al.). Based on this, the hypothesis was formulated that urinary CA19-9 might be a potential biomarker for indicating neurological deficits in children presenting with LUT symptoms. Therefore, this study aimed to compare CA19-9 levels in a larger group of children with neurogenic and non-neurogenic LUT dysfunction.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

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Other recruiting trials for Lower Urinary Track Symptoms

Currently open trials in the same condition.

Other Marmara University trials

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Data sources for this page

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