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NCT06783634

The Effect of High Single Dose of Dexamethasone in Prevention of Post-operative Acute Kidney Injury in Cardiac Surgeries Requiring Cardiopulmonary Bypass

Status unknown Phase 1 Last updated 20 January 2025
What this trial tests

Phase 1 trial testing Dexamethasone in Acute Kidney Injury After Adult Cardiac Surgery in 60 participants. Status unknown.

Timeline
1 February 2025
Primary endpoint
25 March 2025
30 May 2025

Quick facts

Lead sponsorAin Shams University
PhasePhase 1
StatusStatus unknown
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingdouble
Primary purposeother
Enrollment60
Start date1 February 2025
Primary completion25 March 2025
Estimated completion30 May 2025
Sites1 location across Egypt

Drugs / interventions tested

Conditions studied

Sponsor

Ain Shams University

Who can join

Adults 30 to 65, any sex, with Acute Kidney Injury After Adult Cardiac Surgery. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of the current study is to assess the effect of intra operative single high dose dexamethasone (1 mg/kg) in decreasing the incidence of post-operative acute kidney injury after cardiac surgeries with cardiopulmonary bypass

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Molecular mechanisms and therapeutic interventions in acute kidney injury: a literature review.
    He J, Chen Y, Li Y, Feng Y. · · 2025 · cited 5× · PMID 40121405 · DOI 10.1186/s12882-025-04077-4

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Other trials of Dexamethasone

Trials testing the same drug.

Other Ain Shams University trials

Trials by the same sponsor.

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Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06783634.

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