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NCT06782295
The Use of CCK vs PS in Revision TKAs
Phase 4 trial testing Constrained Condylar bearing in Aseptic Loosening of Prosthetic Joint in 170 participants. Currently enrolling.
1 July 2028
Quick facts
| Lead sponsor | Rush University Medical Center |
|---|---|
| Phase | Phase 4 |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 170 |
| Start date | 1 July 2025 |
| Primary completion | 1 July 2028 |
| Estimated completion | 1 July 2038 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Constrained Condylar bearing
- posterior stabilized bearing
Conditions studied
- Aseptic Loosening of Prosthetic Joint — all drugs for Aseptic Loosening of Prosthetic Joint →
- Instability of Prosthetic Joint — all drugs for Instability of Prosthetic Joint →
- Reimplantation for Periprosthetic Joint Infection — all drugs for Reimplantation for Periprosthetic Joint Infection →
- Femoral Revision Indicated — all drugs for Femoral Revision Indicated →
Sponsor
Rush University Medical Center
Who can join
18 and older, any sex, with Aseptic Loosening of Prosthetic Joint or Instability of Prosthetic Joint. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study aims to compare the clinical impact of Constrained Condylar versus Posterior Stabilized Knee (PS) bearings on patient satisfaction and surgical outcomes including mid-term survivorship among patients undergoing revision total knee arthroplasty.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06782295
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other Rush University Medical Center trials
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06782295 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Rush University Medical Center
- Last refreshed: 14 November 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06782295.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing