NCT06781593 (LUCIOPRESS) is a NA clinical trial of Light therapy in Major Depression, sponsored by Hôpital le Vinatier.

Who is sponsoring NCT06781593?

NCT06781593 is sponsored by Hôpital le Vinatier.

What drugs are being tested in NCT06781593?

Interventions in NCT06781593: Light therapy.

What condition does NCT06781593 study?

NCT06781593 studies Major Depression, Sleep Architecture, Obstructive Sleep Apnea, Compliance, Continuous Positive Airway Pressure (CPAP), Light Therapy.

Is NCT06781593 still recruiting?

NCT06781593 is currently recruiting now. Last updated 29 April 2025.

Last reviewed 2025-04-29 · How we verify

NCT06781593: LUCIOPRESS

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Combining Light Therapy and CPAP in Depression

Recruiting now NA Last updated 29 April 2025

What this trial tests

NA trial testing Light therapy in Major Depression in 130 participants. Currently enrolling.

Timeline

17 January 2025

Primary endpoint
30 October 2027

30 October 2027

Quick facts

Lead sponsor	Hôpital le Vinatier
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	130
Start date	17 January 2025
Primary completion	30 October 2027
Estimated completion	30 October 2027
Sites	2 locations across France

Drugs / interventions tested

Light therapy

Conditions studied

Major Depression — all drugs for Major Depression →
Sleep Architecture — all drugs for Sleep Architecture →
Obstructive Sleep Apnea — all drugs for Obstructive Sleep Apnea →
Compliance — all drugs for Compliance →

Sponsor

Hôpital le Vinatier — full company profile →

Who can join

18 and older, any sex, with Major Depression or Sleep Architecture. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

In a double-blind, parallel-group controlled trial, we aim to measure the effect of two weeks of light therapy combined with the CPAP on compliance CPAP in patients with major depressive disorder.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Adjunctive bright light therapy to enhance continuous positive airway pressure adherence in patients with comorbid major depressive disorder and obstructive sleep apnoea syndrome: study protocol for a randomised sham-controlled trial.
El Azzaoui H, Catoire S, Lecharpentier H, Felician J, et al · · 2025 · PMID 41401997 · DOI 10.1136/bmjopen-2025-108669

Verify or expand the search:

Other trials of Light therapy

Trials testing the same drug.

NCT06009289 — Light and Sleep Fragmentation · Phase 4 · not yet recruiting
NCT07462637 — Signature Response to Light Therapy in Unipolar and Bipolar Major Depressive Episode (MDE) · NA · not yet recruiting
NCT06261528 — Study of Circadian Focused Light Therapy in Progressive Multiple Sclerosis · Phase 1 · enrolling by invitation
NCT06165549 — Light Therapy for Internet Gaming Disorder · NA · completed
NCT05391503 — Light Therapy for Obsessive-compulsive Disorder (OCD) · NA · completed

Other recruiting trials for Major Depression

Currently open trials in the same condition.

NCT07031817 — Validation of a Composite Medical Device Using a Blood Biomarker-based Algorithm and MDQ for the Diagnosis of Bipolar Di · NA · recruiting
NCT07184697 — Efficacy and Safety of Task-specific, Biomarker-driven, HD-ctACS inTRD. · NA · active not recruiting
NCT07463911 — Treatment Response In ECT Patients · active not recruiting
NCT06763081 — Pharmacogenomics of Selective Serotonin Reuptake Inhibitor (SSRI)-Induced Behavioural Activation · recruiting
NCT07062783 — Effect of Aerobic Exercise on Biomarkers in Depression · NA · recruiting

Other Hôpital le Vinatier trials

Trials by the same sponsor.

NCT07428200 — Characterization of the Neural Bases of Mental Imagery in Individuals With Borderline Personality Disorder: An EEG Study · NA · not yet recruiting
NCT07384819 — Duration of Moment in Autism · NA · not yet recruiting
NCT06284382 — Interaction Between Early Trauma and Odor-induced Dopamine Release · NA · not yet recruiting
NCT07119671 — Peer-aid and Hope Box · NA · not yet recruiting
NCT06869915 — Homelessness and Prevalence of Neurodevelopmental Disorders · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06781593 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Hôpital le Vinatier
Last refreshed: 29 April 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06781593.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing