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NCT06781021
The Effect of Tranexamic Acid Vs Torniquet on Visual Clarity in Knee Arthroscopic ACL Reconstruction
NA trial testing Tourniquet in ACL Tears in 60 participants. Enrolling by invitation.
1 November 2025
Quick facts
| Lead sponsor | The University of The West Indies |
|---|---|
| Phase | NA |
| Status | ENROLLING BY INVITATION |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 60 |
| Start date | 1 November 2024 |
| Primary completion | 1 November 2025 |
| Estimated completion | 1 February 2026 |
| Sites | 1 location across Jamaica |
Drugs / interventions tested
- Tourniquet
- TXA — full drug profile →
Conditions studied
- ACL Tears — all drugs for ACL Tears →
Sponsor
The University of The West Indies
Who can join
18 and older, any sex, with ACL Tears. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Study Objective: The study aims to determine if tranexamic acid (TXA) is as effective as a tourniquet in improving visual clarity during arthroscopic ACL reconstruction surgery. Study Design: This is a randomized prospective controlled trial involving patients with complete ACL tears. Participants will be randomly assigned to either receive TXA or undergo surgery with a tourniquet. Data Collection: The study will use questionnaires and scales to assess the effects of TXA on visual clarity. Data will be stored securely and analyzed using the SPSS system. Ethical Considerations: Ethical guidelines will be strictly followed, including informed consent, confidentiality, and the right to withdraw from the study at any time without affecting the standard of care. Expected Outcome: The study aims to provide insights into the efficacy of TXA in improving surgical visibility, potentially influencing future protocols in arthroscopic surgeries. Results will be disseminated through academic presentations and publications.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06781021
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06781021 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by The University of The West Indies
- Last refreshed: 17 January 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06781021.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing