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NCT06778538: HPGD-ccRCC
Evaluation of HPGD and SCLO2A1 Expression in Clear Cell Renal Cell Carcinoma Patients
trial testing Immunohistochemistry; WB; PCR in Clear Cell Renal Cell Carcinoma (ccRCC) in 40 participants. Completed in 20 November 2024.
1 November 2024
Quick facts
| Lead sponsor | Shang Panfeng |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 40 |
| Start date | 1 July 2024 |
| Primary completion | 1 November 2024 |
| Estimated completion | 20 November 2024 |
| Sites | 1 location across China |
Drugs / interventions tested
- Immunohistochemistry; WB; PCR
Conditions studied
- Clear Cell Renal Cell Carcinoma (ccRCC) — all drugs for Clear Cell Renal Cell Carcinoma (ccRCC) →
Sponsor
Shang Panfeng
Who can join
18 and older, any sex, with Clear Cell Renal Cell Carcinoma (ccRCC). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study aims to investigate the role of HPGD in clear cell renal cell carcinoma (ccRCC). Specifically, it will focus on HPGD's impact on proliferation, epithelial-mesenchymal transition (EMT), and prognosis. The study will analyze gene expression data from clinical samples and use techniques like RT-qPCR, Western blotting, and immunohistochemistry to assess HPGD expression levels. Additionally, the research will explore the relationship between HPGD and patient survival outcomes. By elucidating HPGD's contribution to cancer progression, the study seeks to identify potential therapeutic targets for improving renal cancer treatment.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06778538
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Clear Cell Renal Cell Carcinoma (ccRCC)
Currently open trials in the same condition.
- NCT07386158 — Pucotenlimab Combination With Vorolanib as Neoadjuvant Therapy for ccRCC · Phase 2 · recruiting
- NCT05176483 — Study of Zanzalintinib in Combination With Immuno-Oncology Agents in Participants With Solid Tumors · Phase 1 · recruiting
- NCT03972657 — A Trial to Find Out if REGN5678 (Nezastomig) is Safe and How Well it Works Alone or in Combination With Cemiplimab for A · Phase 1, PHASE2 · recruiting
- NCT03634540 — A Trial of Belzutifan (PT2977, MK-6482) in Combination With Cabozantinib in Patients With Clear Cell Renal Cell Carcinom · Phase 2 · active not recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06778538 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Shang Panfeng
- Last refreshed: 16 January 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06778538.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing