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NCT06777394
Effects of High Intensity Interval Training in Down Syndrome
NA trial testing High intensity interval training in Down Syndrome in 30 participants. Currently enrolling.
15 January 2025
Quick facts
| Lead sponsor | Riphah International University |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 30 |
| Start date | 27 October 2024 |
| Primary completion | 15 January 2025 |
| Estimated completion | 15 January 2025 |
| Sites | 1 location across Pakistan |
Drugs / interventions tested
- High intensity interval training
- Routine treatmet
Conditions studied
- Down Syndrome — all drugs for Down Syndrome →
Sponsor
Riphah International University
Who can join
Adults 3 to 14, any sex, with Down Syndrome. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Down Syndrome (DS), a genetic condition marked by the presence of an extra chromosome 21, is associated with various cognitive and physical challenges. Children with DS often experience motor development issues, including reduced endurance and decreased trunk stability, which underscores the need for targeted interventions. Common impairments in individuals with DS include hypotonia, ligament laxity, reduced muscle strength, limited muscle co-contraction, poor postural control, and impaired proprioception. This study is driven by a lack of research on the effects of High-Intensity Interval Training (HIIT) in this population, despite its documented benefits in enhancing cardiovascular fitness across other groups. Existing literature supports the benefits of exercise interventions for people with DS, but the application and advantages of HIIT-particularly concerning endurance and trunk stability-are underexplored.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06777394
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of High intensity interval training
Trials testing the same drug.
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- NCT07025694 — Exercise Training Among Children With Cerebral Palsy to Increase Health and Well-being - A Feasibility Study · NA · recruiting
- NCT06509464 — Response Of Metabolic Syndrome Severity Score To High Intenisty Interval Training In Women With Central Obesity. · NA · recruiting
- NCT07046520 — Effects of HIIT on Plasma Volume and Aerobic Capacity in Obese Adolescent Girls · NA · completed
Other recruiting trials for Down Syndrome
Currently open trials in the same condition.
- NCT07416201 — Natural History of Dysregulation and Aging of the Immune System in People With Trisomy 21 With and Without Thymectomy · recruiting
- NCT07484464 — Effects of the Otago Exercise Program on Balance, Endurance, and Motor Coordination in Children With Down Syndrome · NA · recruiting
- NCT07428863 — Effects of Jump Rope on Navicular Drop in Down Syndrome · NA · recruiting
- NCT07260136 — Cervical Spine Abnormalities in Down Syndrome · active not recruiting
- NCT07248449 — Physical Fitness in DS: A Comparison of Cuevas Medak and Rebound Exercises · NA · recruiting
Other Riphah International University trials
Trials by the same sponsor.
- NCT07579585 — Effects of Photobiomodulation in Hemophilia Patients. · NA · recruiting
- NCT07504276 — Tele-Rehabilitation vs Conventional Rehabilitation for Cognitive Improvement in Stroke Survivors. · NA · recruiting
- NCT07484477 — Sedentary Behavior Modification, Cardiopulmonary Function & QOL Post Cardiac Surgery Patients. · NA · not yet recruiting
- NCT07438587 — Comparative Effects of Cadence Training vs Elliptical Training in Cricketers · NA · not yet recruiting
- NCT07484399 — Comparing Effects of HIIT and MICT on Functional Mobility, Muscle Strength, and Quality of Life in Diabetic Patients · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06777394 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Riphah International University
- Last refreshed: 15 January 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06777394.
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