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NCT06777277: CBCT for SIAD
Cognitive-Behavioural Couple Therapy for Sexual Interest/Arousal Disorder
NA trial testing Cognitive-behavioral therapy in Sexual Interest/Arousal Disorder in 170 participants. Currently enrolling.
1 December 2026
Quick facts
| Lead sponsor | Dalhousie University |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 170 |
| Start date | 7 January 2025 |
| Primary completion | 1 December 2026 |
| Estimated completion | 1 December 2028 |
| Sites | 3 locations across Canada |
Drugs / interventions tested
- Cognitive-behavioral therapy
Conditions studied
- Sexual Interest/Arousal Disorder — all drugs for Sexual Interest/Arousal Disorder →
Sponsor
Dalhousie University
Who can join
18 and older, any sex, with Sexual Interest/Arousal Disorder. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Sexual health is a fundamental aspect of quality of life; a satisfying sexual relationship is linked to better physical, psychological, and relationship health and well-being. In fact, people who maintain a satisfying, active sex life over time live longer than those who report lower sexual frequency and satisfaction. Yet problems with sexual function are extremely common, especially for women: chronic difficulties with sexual desire and/or arousal that are personally upsetting-Sexual Interest/Arousal Disorder (SIAD)-affects 7% to 23% of the general population. SIAD is linked to more healthcare costs, depressive symptoms and anxiety, and lower relationship satisfaction. Experts suggest that relationship factors play a critical role in SIAD and couple-based sex therapy is a common approach used by clinicians. However, there are no treatment options available for couples that have been tested in research to confirm that they work. The goal of this three-centre randomized clinical trial is to evaluate the efficacy of a novel 16-session cognitive-behavioural couple therapy (CBCT), offered online to increase accessibility, for an inclusive sample of women with SIAD compared to a waitlist control group. The investigators expect that, compared to a waitlist control group, CBCT will lead to greater improvements in SIAD symptoms (e.g., higher sexual desire/arousal, lower sexual distress) and better sexual, relational, and psychological adjustment for both partners at post-treatment and 6-months later. Given that less than a third of those affected by SIAD access treatment, this study addresses the urgent need for an accessible couple-based treatment for the most common sexual dysfunction. Results will be used by clinicians to provide couples with a scientifically based, accessible treatment option, that will improve their sexual, relationship, and psychological health.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Helping with Outcomes for Low Desire (HOLD): Study protocol for a randomized clinical trial assessing a cognitive-behavioral couple therapy for sexual interest/arousal disorder.
Shimizu JPK, Bouchard KN, Bergeron S, Girouard A, et al · · 2026 · PMID 41840706 · DOI 10.1186/s13063-026-09619-1
Verify or expand the search:
- PubMed search for NCT06777277
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06777277 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Dalhousie University
- Last refreshed: 12 February 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06777277.
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