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NCT06775080
The Use of Propranolol in the Perioperative Period of Resectable Gastrointestinal Tumors
Phase 2 trial testing propranolol (beta-blocker used treat high blood pressure) in Gastrointestinal Tumors in 40 participants. Currently enrolling.
31 December 2026
Quick facts
| Lead sponsor | Huashan Hospital |
|---|---|
| Phase | Phase 2 |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 40 |
| Start date | 1 December 2024 |
| Primary completion | 31 December 2026 |
| Estimated completion | 30 April 2027 |
| Sites | 1 location across China |
Drugs / interventions tested
- propranolol (beta-blocker used treat high blood pressure) — full drug profile →
Conditions studied
- Gastrointestinal Tumors — all drugs for Gastrointestinal Tumors →
Sponsor
Huashan Hospital
Who can join
Adults 18 to 65, any sex, with Gastrointestinal Tumors. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
In this study, perioperative propranolol β-blockade was administered to patients with surgically resectable primary gastrointestinal tumors to explore the safety, efficacy, and alleviation of perioperative psychological stress. At the same time, a multi-omics study was conducted using clinical samples to explore the activation of anti-tumor immune response and its mechanism.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Peripheral Nerves in Cancer: Regulatory Roles and Therapeutic Strategies.
Fu Y, Ge ZS, Cao QY, Li ZH, et al · · 2026 · cited 1× · PMID 41556039 · DOI 10.1002/mco2.70594 -
Cancer Neoaxonogenesis: Mechanisms and Factors Involved in the Recruitment of Peripheral Nerves by Cancer Tissue.
Blasko F, Horvathova L, Hunakova L, Krivosikova L, et al · · 2026 · PMID 42123376 · DOI 10.3390/ijms27093792
Verify or expand the search:
- PubMed search for NCT06775080
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Other Huashan Hospital trials
Trials by the same sponsor.
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- NCT07185373 — Orelabrutinib Combined With Teniposide, Rituximab and Methotrexate for Newly Diagnosed PCNSL · Phase 2, PHASE3 · not yet recruiting
- NCT07075029 — RSV in Acute Respiratory Infection Surveillance Among Community-Dwelling Elderly Aged ≥50 Years in China · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06775080 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Huashan Hospital
- Last refreshed: 14 January 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06775080.
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