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NCT06774612
The Impact of Large Language Models on Diagnostic Reasoning Among LLM-Trained Medical Doctors
NA trial testing ChatGPT-4o in Diagnosis in 60 participants. Completed in 17 May 2025.
17 May 2025
Quick facts
| Lead sponsor | Lahore University of Management Sciences |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 60 |
| Start date | 10 January 2025 |
| Primary completion | 17 May 2025 |
| Estimated completion | 17 May 2025 |
| Sites | 1 location across Pakistan |
Drugs / interventions tested
- ChatGPT-4o
Conditions studied
- Diagnosis — all drugs for Diagnosis →
Sponsor
Lahore University of Management Sciences
Who can join
Eligibility, any sex, with Diagnosis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study aims to evaluate whether large language model-trained medical doctors demonstrate enhanced diagnostic reasoning performance when utilizing ChatGPT-4o alongside conventional resources compared to using conventional resources alone.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
AI-literacy training enhances physician-LLM diagnostic collaboration in a resource-limited setting: a randomized controlled trial
Qazi IA, Ali A, Khawaja AU, Akhtar MJ, et al · · 2025 · DOI 10.1101/2025.06.06.25329104
Verify or expand the search:
- PubMed search for NCT06774612
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Lahore University of Management Sciences trials
Trials by the same sponsor.
- NCT06963957 — Automation Bias in Physician-LLM Diagnostic Reasoning · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06774612 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Lahore University of Management Sciences
- Last refreshed: 17 July 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06774612.
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