Last reviewed · How we verify
NCT06774430
Digital Strategies to Advance Help-Seeking Aim 1 and 2
trial in Clinical High Risk in 25,000 participants. Currently enrolling.
31 May 2028
Quick facts
| Lead sponsor | Columbia University |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 25,000 |
| Start date | 7 April 2025 |
| Primary completion | 31 May 2028 |
| Estimated completion | 31 May 2028 |
| Sites | 1 location across United States |
Conditions studied
- Clinical High Risk — all drugs for Clinical High Risk →
- Early Psychosis — all drugs for Early Psychosis →
- First Episode Psychosis — all drugs for First Episode Psychosis →
Sponsor
Columbia University
Who can join
Adults 12 to 29, any sex, with Clinical High Risk or Early Psychosis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This proposal aims to establish a Digital Laboratory focused on advancing help-seeking and expediting treatment initiation in youth ages 12-29 who are at Clinical High-Risk (CHR) for developing psychosis. Leveraging the Health Action Process Approach (HAPA) model, this study will identify help-seeking subtypes in 25,000 youth who screen positive for psychosis-risk on Mental Health America's national online screening platform, iteratively develop and test theory and data-driven, personalized strategies to advance help-seeking using Micro-Randomized Trials and a Sequential Multiple Assignment Randomized Trial, identify the most accurate CHR screening threshold in an online environment, and link youth, when indicated, to local clinical care via Accelerating Medicines Partnership - Schizophrenia (AMP-SCZ), a NIH funded national network of CHR programs throughout the US. This academic-industry partnership aims to curate one of the largest datasets of youth with CHR, and to develop effective strategies to enhance early help-seeking, in a population where help-seeking is critical and a significant barrier to care.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06774430
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
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Related trials
Other recruiting trials for Clinical High Risk
Currently open trials in the same condition.
- NCT06774417 — Digital Strategies to Advance Help-Seeking - Aim 3 · NA · recruiting
- NCT05905003 — AMP SCZ® Observational Study: PREDICT-DPACC · active not recruiting
Other Columbia University trials
Trials by the same sponsor.
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- NCT05645211 — The AgRP and GH/IGF-1 Axis in Children · not yet recruiting
- NCT07403604 — Effect of Insulin Lowering on Lipogenesis · Phase 1 · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06774430 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Columbia University
- Last refreshed: 2 May 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06774430.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing