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Genetic Studies of Prostate Cancer Aggressiveness and Prognosis
Prostate cancer is the most common form of cancer and the leading cause of cancer-related deaths among men in Sweden. In 2021, over 10,000 men were diagnosed with prostate cancer, and 2,077 died from the disease. Patients diagnosed with early-stage prostate cancer often undergo treatment aimed at curing the disease. However, since the side effects of active treatment are significant, it is crucial to identify new markers for aggressive forms of prostate cancer to better determine who would benefit most from curative treatment. The investigators plan to conduct large-scale genetic studies using blood samples from men with prostate cancer. Specifically, the investigators will search for genetic markers associated with the development of more aggressive prostate cancer forms and markers for clinical progression. The clinical relevance of the identified genetic markers will be tested in a large population-based clinical prostate cancer study (the Stockholm-3 study). The overall goal of this research is to discover new genetic markers for prostate cancer that may lead to more personalized and precise prostate cancer diagnostics.
Details
| Lead sponsor | Karolinska Institutet |
|---|---|
| Status | COMPLETED |
| Enrolment | 2291 |
| Start date | Mon Jan 01 2024 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Tue Dec 31 2024 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Prostate Cancer (Adenocarcinoma)
- Prostate Cancer After a Radical Treatment
Countries
Sweden