Who is sponsoring NCT06773572?

NCT06773572 is sponsored by Biotech Fertility C.A..

What drugs are being tested in NCT06773572?

Interventions in NCT06773572: Autologous Exososomes procedure obtained from the patients' own platelets., Patient group for activated platelet growth factors, the control group.

What condition does NCT06773572 study?

NCT06773572 studies Infertility, Female, Reproductive Techniques, Assisted.

Is NCT06773572 still recruiting?

NCT06773572 is currently completed. Last updated 14 January 2025.

Last reviewed 2025-01-14 · How we verify

NCT06773572: Exosom2024-1

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Use of Autologous Exosomes vs Platelet Growth Factors to Regenerate the Ovary in Women With Infertility (Exosomas2024-1)

Completed NA Last updated 14 January 2025

What this trial tests

NA trial testing Autologous Exososomes procedure obtained from the patients' own platelets. in Infertility, Female in 30 participants. Completed in 30 September 2024.

Timeline

3 January 2024

Primary endpoint
30 September 2024

30 September 2024

Quick facts

Lead sponsor	Biotech Fertility C.A.
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	30
Start date	3 January 2024
Primary completion	30 September 2024
Estimated completion	30 September 2024
Sites	1 location across Venezuela

Drugs / interventions tested

Autologous Exososomes procedure obtained from the patients' own platelets.
Patient group for activated platelet growth factors
the control group — full drug profile →

Conditions studied

Infertility, Female — all drugs for Infertility, Female →
Reproductive Techniques, Assisted — all drugs for Reproductive Techniques, Assisted →

Sponsor

Biotech Fertility C.A.

Who can join

Adults 38 to 48, female only, with Infertility, Female or Reproductive Techniques, Assisted. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Ovarian stromal fibrosis resulting from each ovulation and due to aging is characterized by a decrease in hyaluronic acid concentrations, loss of synthesis and migration proteins CD63 and CD81, decreased miRNA125, miRNA21, miRNA132 and miRNA199. Also, enzymatic alterations affecting kinases and mitochondrial sirtuins SIRT3-5 with increased oxygen free radicals preventing the normal maintenance and development of folliculogenesis, leading to the inability to reproduce at advanced ages and accelerating the onset of pathologies secondary to the decrease of ovarian estrogens. Methodology: An observational, prospective, randomized, comparative, double-blind, analytical pilot study in 30 women between 38 and 46 years of age, with diminished ovarian reserve and who refused the egg donation procedure. Three groups were designated: one for autologous exosomes, one for PRP and one with physiological solution.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Ovarian Aging: Mechanisms, Age-Related Disorders, and Therapeutic Interventions.
Liu X, Zhao Y, Feng Y, Wang S, et al · · 2025 · cited 3× · PMID 41256733 · DOI 10.1002/mco2.70481
Comparative analysis of the use of autologous exosomes and platelet-derived growth factors in women with premature ovarian insufficiency and infertility: A prospective, randomized, observational, analytical study.
Navarro C, Torrecillas Cabrera P, Teppa Garrán A. · · 2025 · cited 3× · PMID 40678344 · DOI 10.1016/j.reth.2025.06.007
Exosomes in oncofertility: emerging roles in chemotherapy-induced reproductive damage and fertility preservation.
Abady MM, Alshehri B, Aldakhil K, Alqassim A, et al · · 2026 · PMID 41961835 · DOI 10.1530/raf-25-0149

Verify or expand the search:

Other recruiting trials for Infertility, Female

Currently open trials in the same condition.

NCT06771401 — Identification of Biomarkers in Cervical Mucus · NA · recruiting
NCT06984081 — CAPA In-vitro Oocyte Maturation · NA · recruiting
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NCT07175571 — SISTER: Sibling Oocyte Insemination With Frozen Sperm From Third Party Donors: Evaluation of Reproductive Techniques · NA · recruiting
NCT06193135 — Usefulness of Corifollitropin α as Alternative to Conventional Daily rFSH Protocols in Oocyte Donors Undergoing Pituitar · NA · recruiting

Other Biotech Fertility C.A. trials

Trials by the same sponsor.

NCT07249411 — In Vitro Oocyte Maturation With Autologous Exosomes in Women · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06773572 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Biotech Fertility C.A.
Last refreshed: 14 January 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06773572.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing