NCT06771635

Effect of Physical Training Program on the Exercise Adherence for Breast Cancer Survivor

Completed NA Last updated 9 January 2026

What this trial tests

NA trial testing concurrent in Breast Cancer Stage I in 62 participants. Completed in 19 July 2019.

Timeline

11 June 2018

Primary endpoint
8 April 2019

19 July 2019

Quick facts

Lead sponsor	Universidad de Burgos
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	supportive care
Enrollment	62
Start date	11 June 2018
Primary completion	8 April 2019
Estimated completion	19 July 2019
Sites	1 location across Spain

Drugs / interventions tested

• concurrent — full drug profile →
• Health Education Session

Conditions studied

• Breast Cancer Stage I — all drugs for Breast Cancer Stage I →
• Breast Cancer Stage II — all drugs for Breast Cancer Stage II →
• Breast Cancer Stage III — all drugs for Breast Cancer Stage III →
• Breast Cancer Stage IIIA — all drugs for Breast Cancer Stage IIIA →

Sponsor

Universidad de Burgos

Who can join

Adults 18 to 65, female only, with Breast Cancer Stage I or Breast Cancer Stage II. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Breast cancer (BC) is one of the most common cancers among women worldwide, with survival rates steadily improving due to advances in early detection and treatment. Despite these improvements, survivors frequently experience long-term side effects such as fatigue, reduced physical function, osteosarcopenia (loss of muscle mass and bone density), and diminished quality of life (QOL). These sequelae often lead to loss of independence, increased frailty, and reduced participation in daily activities. Physical activity, particularly structured and supervised programs, has been shown to mitigate many of these effects. Concurrent training, which combines strength, cardiovascular, and neuromotor exercise, provides a comprehensive approach that targets muscle mass, bone health, and functional mobility. However, adherence to regular physical activity in this population remains low, with most survivors not achieving recommended levels of at least 150 minutes per week of moderate-to-vigorous exercise. This pilot randomized controlled trial aims to evaluate the effects of a 6-week supervised concurrent training program in breast cancer survivors. The program includes 12 supervised sessions designed to improve exercise adherence, physical activity levels, and QOL. The intervention is compared with a control group that receives only a health education session. Outcomes include QOL assessed by the FACT-B questionnaire, physical activity levels measured by the GPAQ, sedentary time, functional fitness, anthropometry, and patient satisfaction. The study is expected to provide evidence that a short-term supervised concurrent training program can improve emotional well-being, preserve QOL, and increase adherence to physical activity in breast cancer survivors.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Effects of a Targeted Concurrent Training Program on the Exercise Adherence in Female Breast Cancer Survivors: A Randomized Controlled Trial.
   Herrero-Zapirain I, Alvarez-Pardo S, Castañeda-Babarro A, García-Heras F, et al · · 2025 · cited 2× · PMID 39997304 · DOI 10.3390/healthcare13040429