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NCT06771427
Exosomes Proteomic for Sjogren's Syndrome and Dry Eye Syndrome
trial testing acupuncture GB20 or GB20 plus BL2 in Dry Eye Syndrome (DES) in 220 participants. Currently enrolling.
30 April 2025
Quick facts
| Lead sponsor | Taipei Veterans General Hospital, Taiwan |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 220 |
| Start date | 16 January 2025 |
| Primary completion | 30 April 2025 |
| Estimated completion | 31 December 2026 |
| Sites | 1 location across Taiwan |
Drugs / interventions tested
- acupuncture GB20 or GB20 plus BL2
- Chinese herbal tea TBDESJS — full drug profile →
Conditions studied
- Dry Eye Syndrome (DES) — all drugs for Dry Eye Syndrome (DES) →
- Sjogren's Syndrome — all drugs for Sjogren's Syndrome →
- Xerophthalmia — all drugs for Xerophthalmia →
Sponsor
Taipei Veterans General Hospital, Taiwan
Who can join
Adults 20 to 75, any sex, with Dry Eye Syndrome (DES) or Sjogren's Syndrome. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
By analyzing the differential proteins in exosomes, this study aims to understand the pathological mechanisms of SJS and DES, identify potential diagnostic and therapeutic methods, and advance the diagnosis and treatment of these diseases.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Clinical applications of extracellular vesicles: recent advances and emerging trends.
Zou Y, Zhou Y, Li G, Dong Y, et al · · 2025 · cited 5× · PMID 41220804 · DOI 10.3389/fbioe.2025.1671963 -
The Potential Application of Exosomes as Therapeutic Agents, Carriers, and Biomarkers in Skin Diseases.
Li W, Li H, Fan L, Zhao R, et al · · 2025 · cited 1× · PMID 41127790 · DOI 10.2147/ijn.s547871 -
Extracellular Vesicles in Autoimmune Diseases: From Diagnostic Biomarkers to Engineered Therapeutics.
Wu Y, Ma H, Zhu T, Huang S, et al · · 2026 · PMID 41677384 · DOI 10.1002/advs.202521802
Verify or expand the search:
- PubMed search for NCT06771427
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Dry Eye Syndrome (DES)
Currently open trials in the same condition.
- NCT06780293 — Laser Acupuncture on Dry Eye and Sjögren's Syndrome-related Dry Eye Symptoms (LADESJS) · Phase 2 · recruiting
Other Taipei Veterans General Hospital, Taiwan trials
Trials by the same sponsor.
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- NCT07400757 — Statin and Vitamin D Treatment in Patients With Thyroid Eye Disease · NA · not yet recruiting
- NCT07362134 — Pulsed-Field Ablation for Recurrent Atypical Atrial Flutter · NA · enrolling by invitation
- NCT07473687 — Feasibility Study of Non-Contact Imaging-Based Physiological Monitoring in the Operating Room · recruiting
- NCT07344207 — GUARD-PH: Guided Use of AI-ECG for Risk Detection of PH in Surgery (GUARD-PH Trial) · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06771427 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Taipei Veterans General Hospital, Taiwan
- Last refreshed: 17 January 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06771427.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing