NCT06768762 (MOST Energized) is a NA clinical trial of Phone Coaching in Knee Replacement, sponsored by University of South Carolina.

Who is sponsoring NCT06768762?

NCT06768762 is sponsored by University of South Carolina.

What drugs are being tested in NCT06768762?

Interventions in NCT06768762: Phone Coaching, Progress reports to providers, 'Hear from Others' Videos, Individualized Feedback, Online exercise program.

What condition does NCT06768762 study?

NCT06768762 studies Knee Replacement.

Is NCT06768762 still recruiting?

NCT06768762 is currently recruiting now. Last updated 7 March 2025.

Last reviewed 2025-03-07 · How we verify

NCT06768762: MOST Energized

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Optimizing a Remote-based Physical Activity Intervention for Adults with Total Knee Replacement

Recruiting now NA Last updated 7 March 2025

What this trial tests

NA trial testing Phone Coaching in Knee Replacement in 336 participants. Currently enrolling.

Timeline

21 January 2025

Primary endpoint
30 December 2028

31 July 2029

Quick facts

Lead sponsor	University of South Carolina
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	factorial
Masking	single
Primary purpose	prevention
Enrollment	336
Start date	21 January 2025
Primary completion	30 December 2028
Estimated completion	31 July 2029
Sites	1 location across United States

Drugs / interventions tested

Phone Coaching
Progress reports to providers
'Hear from Others' Videos
Individualized Feedback
Online exercise program

Conditions studied

Knee Replacement — all drugs for Knee Replacement →

Sponsor

University of South Carolina

Who can join

18 and older, any sex, with Knee Replacement. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The purpose of this study is to identify which supplemental intervention components added to an online exercise program contribute to the greatest increases in physical activity (total MVPA and percent meeting guidelines \[≥150 min/week of MVPA\]) in adults with knee replacement at 6 and 12 months. Secondary outcomes will examine changes in pain and physical function.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Identifying the most effective components of a physical activity intervention for adults with knee replacement: the MOST Energized! study protocol.
Kennerley CL, Coffman DL, Kim Y, Nelson J, et al · · 2026 · PMID 41845290 · DOI 10.1186/s12891-026-09734-9

Verify or expand the search:

Other trials of Phone Coaching

Trials testing the same drug.

NCT05196152 — MomMoodBooster VA Program · NA · completed
NCT04573465 — Pilot Evaluation of Peer-support Coaching to Increase Adherence to Online Self-help for College Mental Health · NA · completed

Other recruiting trials for Knee Replacement

Currently open trials in the same condition.

NCT06968143 — Investigating Patient Satisfaction With Smart Knee Implants · NA · recruiting
NCT07109557 — The Effect of Baduanjin on Patients Undergoing Knee Replacement Surgery · NA · recruiting

Other University of South Carolina trials

Trials by the same sponsor.

NCT06469749 — Theory-based Social Media Intervention for Non-medical Use of Prescription Opioids in Young Adults · NA · not yet recruiting
NCT07340580 — Implementation Facilitation of Exercise is Medicine Greenville · NA · not yet recruiting
NCT07518407 — Dietary Insights and Nutritional Education in Adults on GLP-1 Therapy · NA · not yet recruiting
NCT07340099 — Church Implementation of a Social Support Intervention to Increase Physical Activity in Older African American Adults · NA · not yet recruiting
NCT06024317 — Leveraging Community Health Workers and a Digital Health System to Improve the Timeliness of Child Well Visits · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06768762 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University of South Carolina
Last refreshed: 7 March 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06768762.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing