NCT06766994

The Effect of Two Different Analgesic Techniques on Postoperative Recovery Quality

Recruiting now NA Last updated 30 May 2025

What this trial tests

NA trial testing intrathecal morphine in Abdominal Hysterectomy in 70 participants. Currently enrolling.

Timeline

25 May 2025

Primary endpoint
1 January 2026

1 June 2026

Quick facts

Lead sponsor	Ataturk University
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	other
Enrollment	70
Start date	25 May 2025
Primary completion	1 January 2026
Estimated completion	1 June 2026
Sites	1 location across Turkey (Türkiye)

Drugs / interventions tested

• intrathecal morphine — full drug profile →
• Erector Spinae Plane Block — full drug profile →

Conditions studied

• Abdominal Hysterectomy — all drugs for Abdominal Hysterectomy →

Sponsor

Ataturk University

Who can join

Adults 18 to 65, female only, with Abdominal Hysterectomy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Hysterectomy is one of the most frequently performed surgical procedures after Caesarean section in many countries of the world and involves the removal of the uterine corpus with or without the cervix (total hysterectomy) or without the cervix (subtotal or supracervical hysterectomy) to treat a range of gynecological problems. Hysterectomy is performed abdominally, vaginally with laparotomy, or using minimally invasive techniques (laparoscopy, robotic surgery). The abdominal route for hysterectomy is the preferred route in 60-80% of these surgeries.

Postoperative recovery is a complex condition affected by various factors such as patient characteristics, surgical procedure, and anesthesia. There are many tools available to measure recovery quality. In recent years, the concept of recovery quality perceived by the patient has attracted attention. The Quality of Recovery-40 questionnaire (QoR-40) is an assessment test used to assess recovery quality and health status in the early postoperative stages. QoR-40 consists of 40 questions that evaluate patients' pain, physical comfort, physical independence, psychological support, and emotional state. Quality of Recovery-15 (QoR-15) is a short postoperative recovery scale developed and validated by Stark et al. in 2013. It is an abbreviated version of the QoR-40 scale. It is easy to use because it is shorter and can be completed in a short time. As in QoR-40, it contains 15 questions that evaluate pain, physical comfort, physical independence, psychological support, and emotional state by the patient.

Facilitating the recovery process and optimizing postoperative pain management is an important part of perioperative care. Multimodal analgesia, which combines local anesthesia, peripheral and non-opioid analgesics to minimize systemic opioid requirements and opioid-related side effects, has become increasingly popular. Epidural analgesia, which provides both intraoperative and postoperative analgesia as a complement to general anesthesia for elective abdominal hysterectomy, is an approach applied to achieve balanced and multimodal analgesia. Thus, while the adverse effects of high doses, especially opioid analgesics, applied with a single method are reduced, more effective treatment can be provided for postoperative pain where drugs and other methods alone are insufficient to provide complete analgesia.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.