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NCT06762795
The HIEnome Study: Genome Sequencing for Perinatal HIE
NA trial testing Genome sequencing in Hypoxic Ischemic Encephalopathy of Newborn in 25 participants. Currently enrolling.
31 March 2027
Quick facts
| Lead sponsor | Baylor College of Medicine |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | diagnostic |
| Enrollment | 25 |
| Start date | 15 May 2025 |
| Primary completion | 31 March 2027 |
| Estimated completion | 30 June 2027 |
| Sites | 2 locations across United States |
Drugs / interventions tested
- Genome sequencing
Conditions studied
- Hypoxic Ischemic Encephalopathy of Newborn — all drugs for Hypoxic Ischemic Encephalopathy of Newborn →
- Hypoxic Ischemic Encephalopathy — all drugs for Hypoxic Ischemic Encephalopathy →
- Hypoxic Ischemic Encephalopathy (HIE) — all drugs for Hypoxic Ischemic Encephalopathy (HIE) →
Sponsor
Baylor College of Medicine
Who can join
Adults 0 Days to 1, any sex, with Hypoxic Ischemic Encephalopathy of Newborn or Hypoxic Ischemic Encephalopathy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Perinatal hypoxic-ischemic encephalopathy is a rare severe condition in which neonates present with encephalopathy and a clinical history suggestive of prenatal or perinatal hypoxic-ischemic injury. Emerging evidence suggests that genetic conditions are frequently identified in cases of perinatal HIE; however, it is unclear which neonates with this diagnosis warrant genetic testing. This study will offer clinical genome sequencing to neonates with HIE who are undergoing total body cooling (therapeutic hypothermia) and their parents.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06762795
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Genome sequencing
Trials testing the same drug.
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- NCT03380819 — The VetSeq Study: a Pilot Study of Genome Sequencing in Veteran Care · NA · completed
Other recruiting trials for Hypoxic Ischemic Encephalopathy of Newborn
Currently open trials in the same condition.
- NCT06747260 — Feasibility and Safety of Intranasally Administered Breast Milk in HIE · EARLY_PHASE1 · recruiting
- NCT06563687 — Continuous Glucose Monitoring in HIE · NA · recruiting
- NCT06522581 — Role of Citicoline in Treatment of Neonates With Hypoxic Ischemic Encephalopathy · Phase 1 · recruiting
Other Baylor College of Medicine trials
Trials by the same sponsor.
- NCT07513194 — GPC3 CAR T Cells With IL-15 and IL-21 for Recurrent ATRT and CNS Rhabdoid Tumors (RADIANT) · Phase 1 · not yet recruiting
- NCT05855824 — Toddler Biomarker of Nutrition Study · NA · not yet recruiting
- NCT06738628 — Disposable Endoscope Platform in Third Space Endoscopic Procedures · not yet recruiting
- NCT06834997 — Dronabinol As an Adjunct for Reducing Pain (DARP)-Texas Children's Hospital · Phase 2 · withdrawn
- NCT07387614 — WEB-BASED SUPPORT PROGRAM FOR CAREGIVERS OF VETERANS WITH DEMENTIA DISCHARGED FROM SKILLED NURSING FACILITIES TO HOME · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06762795 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Baylor College of Medicine
- Last refreshed: 1 October 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06762795.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing