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NCT06760663

The Load-velocity Relationship: Neuromuscular Adaptations to Resistance Training

Completed NA Last updated 13 January 2026
What this trial tests

NA trial testing The load-velocity relationship: Neuromuscular adaptations to resistance training in Muscle Hypertrophy in 30 participants. Completed in 30 December 2025.

Timeline
3 March 2025
Primary endpoint
30 December 2025
30 December 2025

Quick facts

Lead sponsorUniversity of Lisbon
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationrandomized
Designsequential
Maskingnone
Primary purposebasic science
Enrollment30
Start date3 March 2025
Primary completion30 December 2025
Estimated completion30 December 2025
Sites1 location across Portugal

Drugs / interventions tested

Conditions studied

Sponsor

University of Lisbon

Who can join

Adults 18 to 30, male only, with Muscle Hypertrophy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Adaptations to resistance training are highly specific and depend on the combination of external loading and the level of individual adaptability. As the relationship between load and velocity of movement is strong and linear, the application of velocity-based training (VBT) has been proposed to enable load adjustments to ensure that exercise is performed at a given intensity independently of several factors such as fatigue. It was recently shown that VBT potentiates increases in muscle strength and power when compared to that seen following a percent-based training (PBT). As the development of muscle strength is explained by the combination of hypertrophy and heightened neural drive, it is important to unravel whether VBT is superior to PBT in eliciting positive adaptations at both these levels or exclusively at one of them. Thus, the aim of this study is to thoroughly compare the neuromuscular adaptations of VBT with the ones found in PBT.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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