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NCT06758843: CMPMRT

Comparing Relative Peripheral Refraction on Myopia Progression

Completed Last updated 7 January 2025
What this trial tests

trial testing measure the axial length, visual acuity, and refraction at follow-up of 6- and 12-month in Myopia in 6,000 participants. Completed in 29 December 2024.

Timeline
23 July 2022
Primary endpoint
29 December 2024
29 December 2024

Quick facts

Lead sponsorFuzhou Southeast Institute of Visual Ophthalmology
StatusCompleted
Study typeOBSERVATIONAL
Enrollment6,000
Start date23 July 2022
Primary completion29 December 2024
Estimated completion29 December 2024
Sites1 location across China

Drugs / interventions tested

Conditions studied

Sponsor

Fuzhou Southeast Institute of Visual Ophthalmology

Who can join

Adults 7 to 17, any sex, with Myopia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The investigators will test our hypothesis that parameters on peripheral defocus can regulate eye growth: For instance, the relative peripheral refraction measured by Multispectral Refraction Topography (MRT) would be significant different between two groups: fast speed and slow speed of axial length elongation (myopia progression) for 1 year with 2-3 follow-ups. The goal of this observation study is to confirm the value of MRT in clinic. Could it predict myopia progression or not? By the parameters on relative peripheral refraction in children myopia, could include any of the following: both genders, 7\~17 years age groups, including healthy volunteers. The main question it aims to answer is: Is any of relative peripheral refraction parameters measured by MRT could guide the clinics for predict myopia progression? Which parameters from MRT could predict the myopia fast progression at baseline ? There is a comparison between groups. Researchers will compare fast myopia progression group versus slow myopia progression group to see if any parameters differs at baseline. Participants will be asked to the collection methods (such as spectacles, orhtokeratology, contact lens) and interventions; And each participant would be followed up for at least 2 times in one year to test the axial length and refractive error as well as parameters with MRT.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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