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NCT06756178
Effect of Remimazolam Versus Dexmedetomidine on the Incidence of Delirium After Elective Cardiac Surgery with Cardiopulmonary Bypass: a Prospective Randomized Controlled Trial
EARLY_PHASE1 trial testing Propofol Group 1 in Delirium - Postoperative in 111 participants. Not yet recruiting.
1 November 2026
Quick facts
| Lead sponsor | Assiut University |
|---|---|
| Phase | EARLY_PHASE1 |
| Status | Not yet recruiting |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | prevention |
| Enrollment | 111 |
| Start date | 10 January 2025 |
| Primary completion | 1 November 2026 |
| Estimated completion | 1 November 2027 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Propofol Group 1
- Remimazolam Intervention — full drug profile →
- Dexmedetomidine Intervention — full drug profile →
Conditions studied
- Delirium - Postoperative — all drugs for Delirium - Postoperative →
Sponsor
Assiut University
Who can join
18 and older, any sex, with Delirium - Postoperative. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The study aims to improve the post-open heart surgery lifestyle and overall experience, as well as assess the incidence of delirium using Remimazolam and Dexmedetomidine.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06756178
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Propofol Group 1
Trials testing the same drug.
- NCT04904965 — Frontal Electroencephalography of Neonatal Patients Under Sedation With Opioids and General Anesthesia With Propofol. · NA · completed
Other recruiting trials for Delirium - Postoperative
Currently open trials in the same condition.
- NCT07411612 — The Association Between Postoperative Inflammatory and Neurological Serum Biomarker Concentrations and Occurrence of Pos · recruiting
- NCT07323940 — Correlation Between Perioperative EEG Variability and Postoperative Delirium Incidence. · recruiting
- NCT06861998 — Preoperative Sleep Intervention on Postoperative Delirium in Infants and Toddlers Undergoing Congenital Heart Surgery · NA · recruiting
- NCT06879431 — Preoperative Sleep Intervention on Postoperative Delirium in School-aged Children Undergoing Congenital Heart Surgery · NA · recruiting
- NCT06894238 — Electroencephalogram Predicts Post-operative Delirium · recruiting
Other Assiut University trials
Trials by the same sponsor.
- NCT07423312 — Lead Exposure and Multiple Sclerosis · not yet recruiting
- NCT07234526 — Usage of Glucose Fluctuations as a Prognostic Marker in Septic Shock Patients · not yet recruiting
- NCT07273214 — Knowledge, Attitude and Practice of Third Trimester Pregnant Mothers Towards Self-Medication in Assiut, Egypt · not yet recruiting
- NCT07194863 — Efficacy of Essential Phospholipid Versus Betaine HCL/L-Glutamic Acid in MAFLD · not yet recruiting
- NCT07053709 — Screening for Hyperuricemia in Patients With Metabolic Associated Fatty Liver Disease (MAFLD) · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06756178 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Assiut University
- Last refreshed: 1 January 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06756178.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing