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Effect of L-carnitine Supplementation on Disease Activity in Rheumatoid Arthritis Patients
This study aims to evaluate the effect of l-carnitine as add- on therapy for improving the outcome in rheumatoid arthritis patients.
Details
| Lead sponsor | German University in Cairo |
|---|---|
| Phase | Phase 2 |
| Status | RECRUITING |
| Enrolment | 60 |
| Start date | 2024-12-31 |
| Completion | 2025-06 |
Conditions
- Rheumatoid Arthritis (RA)
Interventions
- Carnitine
- Disease-modifying anti-rheumatic drugs
Primary outcomes
- change in DAS28 ESR for both arms — From enrollment to the end of trial at 12 weeks
DAS 28-ESR is a score used to measure disease activity in RA patients. it is calculated using an equation where number of tender joints ( out of 28 joints) , number of swollen joints ( out of 28 joints) , patient assessment of disease activity ( using visual analogue scale from zero to 10) and ESR level are used as inputs to give DAS 28-ESR as output . the score will be measured to all participants both at baseline and at end of study. Higher scores indicate higher disease activity .
Countries
Egypt