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NCT06753500: ANB
Intraoperative Autonomic Blockade for Laparoscopic Cholecystectomy
Phase 4 trial testing Autonomic neural blockade in Visceral Pain in 60 participants. Currently enrolling.
1 November 2025
Quick facts
| Lead sponsor | Universidad Simón Bolívar |
|---|---|
| Phase | Phase 4 |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | prevention |
| Enrollment | 60 |
| Start date | 15 January 2025 |
| Primary completion | 1 November 2025 |
| Estimated completion | 4 November 2025 |
| Sites | 2 locations across Colombia |
Drugs / interventions tested
- Autonomic neural blockade
Conditions studied
- Visceral Pain — all drugs for Visceral Pain →
- Analgesia — all drugs for Analgesia →
- Opioid Use — all drugs for Opioid Use →
- Postoperative Nausea — all drugs for Postoperative Nausea →
Sponsor
Universidad Simón Bolívar — full company profile →
Who can join
18 and older, any sex, with Visceral Pain or Analgesia. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study proposes infiltrating the hepatoduodenal ligament and the serosal reflection of the gallbladder cystic plate with a combination of Bupivacaine (a long-acting local anesthetic) and Dexamethasone (a corticosteroid). This technique aims to block the hepatic branches of the celiac plexus to improve visceral pain control and its associated clinical manifestations, reduce analgesic requirements, and lower readmission rates, thereby facilitating recovery.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06753500
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Visceral Pain
Currently open trials in the same condition.
- NCT07209566 — A Research Study Exploring How Musculoskeletal Function and the Autonomic Nervous System Relate to Visceral Pain in Wome · NA · recruiting
- NCT06973122 — Paragastric Neural Blockade and Laparoscopic Assisted Transversus Abdominis Plane Block on Visceral Pain After Surgery · NA · recruiting
- NCT06517069 — Effect of TEAS Combined With Oxycodone on Postoperative Visceral Pain in Gynecologic Laparoscopic Patients · NA · recruiting
- NCT04907643 — Virtual Reality for GI Cancer Pain to Improve Patient Reported Outcomes · NA · recruiting
Other Universidad Simón Bolívar trials
Trials by the same sponsor.
- NCT06137924 — Intraoperative Autonomic Neural Blockade · Phase 3 · unknown
- NCT05668845 — Paragastric Autonomic Neural Blockade as Part of Combined Anesthesia. · NA · completed
- NCT05353426 — Paragastric Autonomic Blockade to Prevent Visceral Pain After Laparoscopic Sleeve Gastrectomy · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06753500 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Universidad Simón Bolívar
- Last refreshed: 28 January 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06753500.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing