NCT06753344: Y-PRIME

Youth Promotion of Resilience Involving Mental E-health

Recruiting now NA Last updated 25 March 2025

What this trial tests

NA trial testing Intervention app in Mental Well-being in 1,800 participants. Currently enrolling.

Timeline

10 January 2025

Primary endpoint
31 March 2028

31 March 2028

Quick facts

Lead sponsor	University of British Columbia
Phase	NA
Status	Recruiting now
Study type	INTERVENTIONAL
Allocation	non randomized
Design	parallel
Masking	none
Primary purpose	prevention
Enrollment	1,800
Start date	10 January 2025
Primary completion	31 March 2028
Estimated completion	31 March 2028
Sites	1 location across Vietnam

Drugs / interventions tested

• Intervention app

Conditions studied

• Mental Well-being — all drugs for Mental Well-being →
• Resilience — all drugs for Resilience →
• Population Study — all drugs for Population Study →

Sponsor

University of British Columbia

Who can join

Adults 15 to 16, any sex, with Mental Well-being or Resilience. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

There is a critical gap in access to mental health promotion, prevention and support among youth worldwide, especially in low and middle-income countries like Vietnam. The Y-PRIME Study aims to respond to this gap by co-designing with Vietnamese youth a mobile app that delivers life skills and self-management skills intervention to promote mental well-being in grade 10 Vietnamese students. Working with the Vietnam Youth Advisory Council (V-YAC) to adapt and co-design the intervention and app ensure that the intervention will be culturally appropriate and relevant to Vietnamese youth. The goal of the current phase is to test this intervention with grade 10 students across three provinces (Hanoi, Thai Binh, and Hung Yen) to assess:

1. Whether the app helps to improve mental well-being and resilience among youth in Vietnam and helps to reduce factors that might increase the risk of poor mental well-being, like stress related to school and other pressures
2. Whether the app can be delivered in Vietnamese schools
3. Whether Vietnamese youth and school staff think the app is appropriate and appealing for youth in order to scale-up the model across the country

The control group (meaning they do not have access to the app-based intervention) will complete the outcome survey at baseline, 6 months, and 12 months. After 12 months, they will gain access to the intervention app (at the same time as the experimental group) but no more data will be collected. The intervention group will use the app at their own pace for 1 year while completing the same survey at baseline, 6 months, and 12 months marks. Afterwards, students and school health staff will be invited to a focus group discussion to talk about their experience using the app.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Promoting mental well-being among secondary school students in Vietnam using the Y-MIND app: A protocol for a hybrid type 2, sequence pre-post, quasi-experimental study.
   Murphy JK, Nguyen VC, Linh DT, Xie H, et al · · 2025 · PMID 41056276 · DOI 10.1371/journal.pone.0332875