Last reviewed · How we verify
NCT06752577
Safety and Tolerability of Vertebral Bone Marrow-derived Mesenchymal Stem Cells (BM-MSC) in Real World Scenarios of Patients With Chronic Kidney Disease (CKD)
trial testing Allogeneic, vertebral bone marrow-derived mesenchymal stem cells (MSC) in Chronic Kidney Diseases in 75 participants. Currently enrolling.
31 December 2030
Quick facts
| Lead sponsor | Mayo Clinic |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 75 |
| Start date | 22 December 2024 |
| Primary completion | 31 December 2030 |
| Estimated completion | 31 December 2031 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Allogeneic, vertebral bone marrow-derived mesenchymal stem cells (MSC) — full drug profile →
Conditions studied
- Chronic Kidney Diseases — all drugs for Chronic Kidney Diseases →
- Kidney Transplant — all drugs for Kidney Transplant →
Sponsor
Mayo Clinic
Who can join
18 and older, any sex, with Chronic Kidney Diseases or Kidney Transplant. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this protocol is to treat an intermediate-sized population with chronic kidney disease (CKD) including kidney transplant recipients. The protocol uses allogeneic bone marrow-derived mesenchymal stem cells (MSCs). MSC infusion may be delivered 1) intravenous or 2) intravenous plus intra-arterial to both kidneys. Individuals will have subsequent follow up for safety evaluations. Repeat dosing is allowed.
Publications & conference data
2 peer-reviewed publications reference this trial (live from Europe PMC):
-
Uremic Toxins, CKD, and Cognitive Dysfunction.
Andrews TD, Day GS, Irani SR, Kanekiyo T, et al · · 2025 · cited 10× · PMID 40009460 · DOI 10.1681/asn.0000000675 -
Integrative Approaches to Treating Cellular Senescence in Kidney Disease.
Misawa T, A A, Hickson LJ, Wolfram J. · · 2026 · PMID 41831318 · DOI 10.1002/advs.202519392
Verify or expand the search:
- PubMed search for NCT06752577
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06752577 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Mayo Clinic
- Last refreshed: 28 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06752577.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing