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NCT06750900: CLEVER BODY
Visual Feedback Manipulation in Virtual Reality Alters Extension-evoked Pain Perception in Chronic LBP
trial testing NORMAL CONDITION in Chronic Low-back Pain (cLBP) in 50 participants. Completed in 7 January 2025.
18 December 2024
Quick facts
| Lead sponsor | Cardenal Herrera University |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 50 |
| Start date | 4 December 2024 |
| Primary completion | 18 December 2024 |
| Estimated completion | 7 January 2025 |
| Sites | 1 location across Spain |
Drugs / interventions tested
- NORMAL CONDITION
- UNDERSTATED CONDITION
- OVERSTATED CONDITION
Conditions studied
- Chronic Low-back Pain (cLBP) — all drugs for Chronic Low-back Pain (cLBP) →
Sponsor
Cardenal Herrera University
Who can join
Adults 18 to 65, any sex, with Chronic Low-back Pain (cLBP). Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study investigates the potential to modify movement-evoked pain in individuals with chronic low back pain (LBP) by manipulating visual proprioceptive feedback through virtual reality (VR). Fifty patients with non-specific chronic LBP are planned to participate. Participants perform lumbar spine extension until pain onset under three conditions: accurate visual feedback (control), feedback showing 10% less movement (E-), and feedback showing 10% more movement (E+). Lumbar range of motion (ROM) is measured using a 3-space Fastrack motion analysis system. The study also explores whether individuals with higher pain levels, kinesiophobia, disability, or catastrophising are more susceptible to VR feedback manipulation. Pain thresholds, pain intensity, kinesiophobia, disability, and catastrophising levels are assessed.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Visual feedback manipulation in virtual reality alters movement-evoked pain perception in chronic low back pain.
Jordán-López J, Arguisuelas MD, Doménech J, Peñalver-Barrios ML, et al · · 2025 · cited 2× · PMID 40596530 · DOI 10.1038/s41598-025-08094-z
Verify or expand the search:
- PubMed search for NCT06750900
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Chronic Low-back Pain (cLBP)
Currently open trials in the same condition.
- NCT07388134 — Virtual Reality Based High-intensity Interval Training in Chronic Low Back Pain · NA · active not recruiting
- NCT07334782 — Effects of Vertebral Axial Loading Walking Combined With Core Stabilization Exercises in Individuals With Chronic Low Ba · NA · active not recruiting
- NCT07280806 — Biopsychosocial Model-based Care Versus Routine Physical Therapy in Chronic Back Pain · NA · recruiting
- NCT07133139 — Treatment Validation for Myofascial Pain · NA · recruiting
- NCT07211464 — Acceptance and Commitment Therapy Plus Exercise for Older People With Chronic Low-back Pain: A Pragmatic Cluster Randomi · NA · recruiting
Other Cardenal Herrera University trials
Trials by the same sponsor.
- NCT07471269 — Online Pain Neuroscience Education For Fear Of Childbirth. · NA · recruiting
- NCT07373938 — Carotid Wall Texture as a Cardiovascular Risk Biomarker in Type 2 Diabetes Mellitus · recruiting
- NCT07499856 — Intradialytic Exercise Program Supported by Audiovisual Media Combined With Mindfulness · NA · enrolling by invitation
- NCT07275112 — Cross-cultural an Reliability and Validity Evaluation of TENDINS-A in Spain · completed
- NCT07133581 — Design and Validation of FEXO: A Playful Exercise Program for Institutionalized Frail Older Adults · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06750900 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Cardenal Herrera University
- Last refreshed: 11 February 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06750900.
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