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NCT06750770

Development and Validation of a Clinical Risk Prediction Model for Early Acute Kidney Injury Within 48 Hours After Liver Transplantation

Completed Last updated 27 December 2024
What this trial tests

trial testing KDIGO CRITERIA in Acute Kidney Injury in 453 participants. Completed in 15 December 2022.

Timeline
1 January 2018
Primary endpoint
15 October 2022
15 December 2022

Quick facts

Lead sponsorBeijing Tsinghua Chang Gung Hospital
StatusCompleted
Study typeOBSERVATIONAL
Enrollment453
Start date1 January 2018
Primary completion15 October 2022
Estimated completion15 December 2022
Sites1 location across China

Drugs / interventions tested

Conditions studied

Sponsor

Beijing Tsinghua Chang Gung Hospital

Who can join

18 and older, any sex, with Acute Kidney Injury or Liver Transplantation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Acute kidney injury (AKI) is a common complication after liver transplantation, with an incidence of 12.7-95%. The occurrence of acute kidney injury after transplantation is related to the poor prognosis of patients, which significantly increases the length of hospital stay, hospitalization costs and mortality of patients. Early recognition of acute kidney injury after transplantation is of great significance. Therefore, by collecting preoperative and intraoperative variables, this study intends to establish and verify a clinical risk prediction model for early AKI after liver transplantation, in order to provide clinicians with a visual prediction tool to identify patients with high risk of early AKI after liver transplantation immediately after the operation, so as to start clinical intervention as soon as possible and improve the prognosis of patients.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Early Prediction of Acute Kidney Injury Following Liver Transplantation: Development and Validation of a Clinical Risk Model.
    Wei Y, Qi Z, Wu W, Feng C, et al · · 2026 · PMID 41048885 · DOI 10.1016/j.jceh.2025.103179

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Other recruiting trials for Acute Kidney Injury

Currently open trials in the same condition.

Other Beijing Tsinghua Chang Gung Hospital trials

Trials by the same sponsor.

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Data sources for this page

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