NCT06750107 is a Phase 3 clinical trial of Safe South Africa in Intervention, sponsored by Brown University.

Who is sponsoring NCT06750107?

NCT06750107 is sponsored by Brown University.

What drugs are being tested in NCT06750107?

Interventions in NCT06750107: Safe South Africa.

What condition does NCT06750107 study?

NCT06750107 studies Intervention, Control.

Is NCT06750107 still recruiting?

NCT06750107 is currently active, enrolled. Last updated 2 February 2026.

Last reviewed 2026-02-02 · How we verify

NCT06750107

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Testing the Efficacy of Safe South Africa

Active, enrolled Phase 3 Last updated 2 February 2026

What this trial tests

Phase 3 trial testing Safe South Africa in Intervention in 836 participants. Participants enrolled and being followed up; not accepting new ones.

Timeline

22 January 2025

Primary endpoint
30 April 2028

30 December 2028

Quick facts

Lead sponsor	Brown University
Phase	Phase 3
Status	Active, enrolled
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	prevention
Enrollment	836
Start date	22 January 2025
Primary completion	30 April 2028
Estimated completion	30 December 2028
Sites	1 location across South Africa

Drugs / interventions tested

Safe South Africa

Conditions studied

Intervention — all drugs for Intervention →
Control — all drugs for Control →

Sponsor

Brown University

Who can join

Adults 15 to 17, male only, with Intervention or Control. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

In this study, investigators will examine the efficacy of Safe South Africa, a behavioral intervention that is developmentally- and gender-tailored to prevent human immunodeficiency virus (HIV) and intimate partner violence (IPV) among adolescent boys. South Africa faces some of the highest global rates of HIV and IPV with sustained high incidence of HIV and alarming rates of IPV among adolescents and thus, is an ideal site to advance prevention science to tackle these urgent public health priorities. Testing the efficacy of an integrated intervention to prevent HIV risk behavior and IPV for adolescent boys can support optimal health for young people, their future partners, and society.

Publications & conference data

No peer-reviewed publications indexed yet for this trial.

Verify or expand the search:

Other trials of Safe South Africa

Trials testing the same drug.

NCT03179982 — Integrated Prevention of HIV Risk and Intimate Partner Violence Among Adolescents in South Africa · NA · completed

Other recruiting trials for Intervention

Currently open trials in the same condition.

NCT06978959 — Family Navigator Plus for Foster Parents · NA · recruiting
NCT07361211 — A Multifaceted Intervention to Reduce Obesity Among Preschool Children: Study Protocol for a Randomized Controlled Trial · NA · active not recruiting
NCT07113626 — Adapting An Evidence-Based Intervention To Improve HIV Testing And PrEP Uptake In Vietnam · NA · recruiting
NCT06515574 — Effect of Developmental Care on Very Low Birth Weight Infants · NA · recruiting
NCT06454773 — To Evaluate the Impact of Consumption of Bioactive Compounds Extracted From Hemp Hull and Black Pepper on Fasting Blood · Phase 3 · recruiting

Other Brown University trials

Trials by the same sponsor.

NCT07502872 — TPG: Tafasitamab, Polatuzumab Vedotin, and Glofitamab as First-line Therapy for Diffuse Large B-cell Lymphoma and High-g · Phase 2 · not yet recruiting
NCT07118618 — Probenecid Administration for Alcohol Craving and Consumption · Phase 2 · recruiting
NCT07398443 — Using Novel Behavioral Economic Measures to Characterize Dual Marijuana and Tobacco Use in Young Adults · NA · recruiting
NCT05901766 — Effect of Iodine-containing Multiple Micronutrient During Lactation on Infant Neurodevelopment · Phase 4 · not yet recruiting
NCT06974604 — Preventing Dato-DXd Associated Stomatitis With Dexamethasone Mouthwash, TROPION-DM · Phase 2 · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06750107 (US National Library of Medicine, public domain)
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Brown University
Last refreshed: 2 February 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06750107.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing