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NCT06745778
Evolution of Intracardiac Electrograms Recorded by Left Bundle Branch Pacing Lead in Patients With ICD or CRT-D
trial in Ventricular Tachycardia (VT) in 50 participants. Currently enrolling.
31 December 2025
Quick facts
| Lead sponsor | Medtronic Cardiac Rhythm and Heart Failure |
|---|---|
| Status | Recruiting now |
| Study type | OBSERVATIONAL |
| Enrollment | 50 |
| Start date | 26 February 2025 |
| Primary completion | 31 December 2025 |
| Estimated completion | 30 June 2026 |
| Sites | 2 locations across China |
Conditions studied
- Ventricular Tachycardia (VT) — all drugs for Ventricular Tachycardia (VT) →
- Ventricular Fibrillation — all drugs for Ventricular Fibrillation →
Sponsor
Medtronic Cardiac Rhythm and Heart Failure — full company profile →
Who can join
18 and older, any sex, with Ventricular Tachycardia (VT) or Ventricular Fibrillation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this observational study is to investigate the changes of LBB EGM during daily activities and overdrive pacing at the time of peri-implantation and up to 6-month follow-ups of ICD/CRT-D patients. The main question it aims to answer is: • Does the LBBP lead can provide accurate, stable, and valid EGM for ICD/CRT-D sensing and detection of ventricular tachyarrhythmia events? In each patient intracardiac EGMs of LBBP lead will be collected by ambulatory Holter monitor at the time of peri-implantation and up to 6-month follow-up. EGM collection will be collected at resting and walking conditions and overdrive pacing.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06745778
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Ventricular Tachycardia (VT)
Currently open trials in the same condition.
- NCT06990139 — Ventricular Tachycardia Ablation Through Radiation Therapy Consortium: Concept Description of an Observational Retrospec · active not recruiting
- NCT06922214 — VT ART Consortium: Radioablation for Ventricular Tachycardia · NA · active not recruiting
- NCT07196176 — Electrophysiological Registry Duesseldorf · recruiting
Other Medtronic Cardiac Rhythm and Heart Failure trials
Trials by the same sponsor.
- NCT06910059 — The CT-verified Data Collection Study to Investigate the Correlation Between the Leadless Pacemaker Tip Location and Ech · active not recruiting
- NCT06540521 — Bolt CSP-M Holter Study · recruiting
- NCT06038123 — China 3T MRI Study · NA · completed
- NCT06089694 — Crome/Cobalt Respiration Study · completed
- NCT05766462 — Allometric-Pace Study · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06745778 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Medtronic Cardiac Rhythm and Heart Failure
- Last refreshed: 1 May 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06745778.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing