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NCT06745375: FLOSS
Assessment of the Relationship of Soft Contact Lens Fit and Power (Fit & Lens pOwer Soft lenSes)
NA trial testing contact lens wear in Healthy Participants Study in 38 participants. Enrolling by invitation.
31 August 2026
Quick facts
| Lead sponsor | Aston University |
|---|---|
| Phase | NA |
| Status | ENROLLING BY INVITATION |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | other |
| Enrollment | 38 |
| Start date | 30 January 2026 |
| Primary completion | 31 August 2026 |
| Estimated completion | 31 December 2026 |
| Sites | 1 location across United Kingdom |
Drugs / interventions tested
- contact lens wear
Conditions studied
- Healthy Participants Study — all drugs for Healthy Participants Study →
- Contact Lens Wear — all drugs for Contact Lens Wear →
- Contact Lens Fit — all drugs for Contact Lens Fit →
Sponsor
Aston University
Who can join
Adults 18 to 60, any sex, with Healthy Participants Study or Contact Lens Wear. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to evaluate whether altering the optical power (in dioptres) of a contact lens affects both vision and lens fit. As the majority of modern contact lens wearers prefer daily disposable soft lenses, the trial lenses used in this study-provided by CooperVision-reflect this trend, representing nearly 80% of the current UK market. This study aims to generate data supporting the use of contact lenses with powers that do not precisely match a participant's visual prescription (within ±2.00 dioptres) as a viable temporary alternative when the exact required power is unavailable. At present, there is no published literature in the context of modern contact lens design that compares the fitting characteristics of 'fit-for-purpose' lenses with those of lenses from the same design family that would not typically be selected due to power mismatch.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06745375
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Currently open trials in the same condition.
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Other Aston University trials
Trials by the same sponsor.
- NCT07535749 — The Effect of Myopia-Control Contact Lenses in New Zealand Chinese Children · Phase 3 · recruiting
- NCT07378397 — OPM MEG in Pre-surgical Mapping for Patients With Epilepsy · enrolling by invitation
- NCT06615453 — Impact of Tixel Treatment on Symptoms and Signs in Patients With Dry Eye Disease · NA · recruiting
- NCT06163989 — Protecting the Eyes of Gamers With Lubricating Eyedrops · NA · recruiting
- NCT06371300 — Photobiomodulation With REd vs BluE Light (REBEL) · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06745375 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Aston University
- Last refreshed: 21 January 2026
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06745375.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing