Who is sponsoring NCT06741748?

NCT06741748 is sponsored by Chinese University of Hong Kong.

What drugs are being tested in NCT06741748?

Interventions in NCT06741748: Direct Warming Method, Conventional Multi-step Thawing Method.

What condition does NCT06741748 study?

NCT06741748 studies Frozen Embryo Transfer (FET), Assisted Reproductive Techniques, In Vitro Fertilization (IVF), Cryopreservation of Embryos, Pregnancy Outcome After in Vitro Fertilization (IVF).

Is NCT06741748 still recruiting?

NCT06741748 is currently not yet recruiting. Last updated 11 March 2025.

Last reviewed 2025-03-11 · How we verify

NCT06741748: DW-FET-RCT

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Direct Warming Frozen Embryo Transfer Outcomes in Assisted Reproductive Technology

Not yet recruiting NA Last updated 11 March 2025

What this trial tests

NA trial testing Direct Warming Method in Frozen Embryo Transfer (FET) in 578 participants. Not yet recruiting.

Timeline

1 September 2025

Primary endpoint
31 October 2026

31 October 2027

Quick facts

Lead sponsor	Chinese University of Hong Kong
Phase	NA
Status	Not yet recruiting
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	578
Start date	1 September 2025
Primary completion	31 October 2026
Estimated completion	31 October 2027
Sites	3 locations across Hong Kong, United Kingdom

Drugs / interventions tested

Direct Warming Method
Conventional Multi-step Thawing Method

Conditions studied

Frozen Embryo Transfer (FET) — all drugs for Frozen Embryo Transfer (FET) →
Assisted Reproductive Techniques — all drugs for Assisted Reproductive Techniques →
In Vitro Fertilization (IVF) — all drugs for In Vitro Fertilization (IVF) →
Cryopreservation of Embryos — all drugs for Cryopreservation of Embryos →

Sponsor

Chinese University of Hong Kong

Who can join

Adults 18 to 45, female only, with Frozen Embryo Transfer (FET) or Assisted Reproductive Techniques. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The goal of this clinical trial is to evaluate whether the direct warming method for frozen embryo transfers (FET) can improve live birth and pregnancy outcomes in women aged 18-45 undergoing IVF treatments. The main questions it aims to answer are: * Does the direct warming method achieve a similar or higher clinical success rate for FET compared to the conventional multi-step method? * Is the direct warming method more cost-effective than the conventional method? Researchers will compare the direct warming method to the conventional multi-step method to see if the former leads to better pregnancy outcomes and reduced procedural time. Participants will: * Undergo either the one-step or conventional embryo thawing procedure. * Complete standard clinical follow-ups for pregnancy, including ultrasound scans and pregnancy tests.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Direct warming and rehydration method in frozen embryo transfer: study protocol for a pragmatic, multi-center, double-blinded, two-arm randomized controlled trial.
Wu W, Xu M, Fung KK, Zhang L, et al · · 2026 · PMID 42152121 · DOI 10.1186/s13063-026-09663-x

Verify or expand the search:

Other recruiting trials for Frozen Embryo Transfer (FET)

Currently open trials in the same condition.

NCT07358468 — Impact Of FET Preparation Protocol On Endometrial Peristalsis: A Prospective Cohort Study · recruiting
NCT07088640 — Single Step Protocol and Multi-step Warming Protocol for Blastocyst FET · NA · recruiting
NCT06875752 — Is There a Need for Luteal Support in Modified Natural Cycle Frozen Embryo Transfer Cycles · Phase 4 · recruiting
NCT07257250 — Levothyroxine Treatment and IVF Outcomes in Women With Subclinical Hypothyroidism: A Target Trial Emulation · recruiting

Other Chinese University of Hong Kong trials

Trials by the same sponsor.

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NCT07288671 — Nostalgia Intervention on Alleviating Loneliness Amongst Older Adults · NA · not yet recruiting
NCT07256457 — Postoperative Pulmonary Function Assessment Based on Deep Learning Study · NA · not yet recruiting
NCT06904209 — Can Artificial Intelligence Reduce Consumption of Standard High Volume Bowel Preparation Regimen Among Older Population, · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT06741748 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Chinese University of Hong Kong
Last refreshed: 11 March 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06741748.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing