Who is sponsoring HEART-FREE?

HEART-FREE is sponsored by Paris Translational Research Center for Organ Transplantation.

What condition does HEART-FREE study?

HEART-FREE studies Heart Transplantation, Rejection Heart Transplant.

What is the status of HEART-FREE?

HEART-FREE is currently COMPLETED.

Last reviewed 2025-01-03 · How we verify

Evaluation of the Added Clinical Value of Donor-derived Cell-free DNA for the Monitoring of Cardiac Allograft Rejection. (HEART-FREE)

NCT06740578 COMPLETED

The goal of this observational study is to assess the clinical added value of donor-derived cell-free DNA (dd-cfDNA) to monitor cardiac allograft rejection. The main question it aims to answer is whether dd-cfDNA is independently associated with rejection and if it allows a significant improvement in individual risk stratification of rejection on top of a robust predictive model based on standard clinical and biological predictive variables.

Details

Lead sponsor	Paris Translational Research Center for Organ Transplantation
Status	COMPLETED
Enrolment	320
Start date	Fri Oct 01 2021 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Tue Oct 31 2023 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

Heart Transplantation
Rejection Heart Transplant

Countries

France