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NCT06739343
Comparison of Phaco-Trabeculectomy and MSICS-Trab in Cataract and Glaucoma Patients
NA trial testing PHACO-Trabeculectomy in Cataract in 122 participants. Completed in 30 September 2024.
30 September 2024
Quick facts
| Lead sponsor | Emeka John Dingwoke |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 122 |
| Start date | 21 September 2022 |
| Primary completion | 30 September 2024 |
| Estimated completion | 30 September 2024 |
| Sites | 1 location across Nigeria |
Drugs / interventions tested
- PHACO-Trabeculectomy
- MSICS-Trabeculectomy
Conditions studied
Sponsor
Emeka John Dingwoke
Who can join
18 and older, any sex, with Cataract or Glaucoma. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this interventional study is to compare the outcomes of two surgical techniques, Phaco-Trabeculectomy and Manual Small Incision Cataract Surgery (MSICS) with Trabeculectomy, in patients with coexisting cataract and glaucoma at ECWA Eye Hospital, Kano, Nigeria. The study aims to evaluate which technique offers better intraocular pressure (IOP) control, visual acuity improvement, and complication rates postoperatively. The main questions the study seeks to answer are: Does Phaco-Trabeculectomy provide superior IOP control compared to MSICS-Trabeculectomy in patients with coexisting cataract and glaucoma? Which technique is associated with fewer postoperative complications? How do the visual outcomes compare between the two techniques? Participants will be randomly assigned to undergo one of the two surgical techniques based on a predefined protocol. Data will be collected on intraoperative and postoperative parameters, including IOP, visual acuity, and the incidence of complications, with follow-ups extending over a 12-month period. This study aims to provide evidence to guide clinicians in selecting the most effective and safe surgical approach for managing patients with cataract and glaucoma in resource-limited settings.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Phaco-trabeculectomy versus MSICS-trabeculectomy for coexisting cataract and glaucoma: visual and IOP outcomes from a randomized trial in Nigeria.
Munaje MI, Aribaba OT, Atima MO, Idakwo U, et al · · 2025 · PMID 41194003 · DOI 10.1186/s12886-025-04482-1
Verify or expand the search:
- PubMed search for NCT06739343
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06739343 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Emeka John Dingwoke
- Last refreshed: 18 December 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06739343.
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