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NCT06738290
Predicting Motor Learning of an Upper Limb Task Based on Behavioral and Disease-specific Characteristics in Patients With Parkinson's Disease
trial testing Targeted home-based touchscreen training in Parkinson Disease in 100 participants. Completed in 13 December 2024.
12 December 2024
Quick facts
| Lead sponsor | KU Leuven |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 100 |
| Start date | 10 January 2022 |
| Primary completion | 12 December 2024 |
| Estimated completion | 13 December 2024 |
| Sites | 1 location across Belgium |
Drugs / interventions tested
- Targeted home-based touchscreen training
Conditions studied
- Parkinson Disease — all drugs for Parkinson Disease →
Sponsor
KU Leuven — full company profile →
Who can join
Eligibility, any sex, with Parkinson Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Manual dexterity deficits and loss of motor automaticity are commonly seen in patients with Parkinson's disease (PD). Amongst these problems, using a touchscreen is becoming increasingly burdensome. In addition, a variety of non-motor symptoms, including cognitive impairment have a significant impact on the quality of life of patients with PD which will also affect the use of mobile devices. As the degradation of dopaminergic neurons in the striatum results in an impaired capacity for motor learning and more specifically for consolidation in motor memory, the investigators want to unravel the remaining rehabilitation potential in this patient group. Recent work on the consolidation of an intensive writing training program from our group, indicated inconsistent and variable results on retention of learning gains, which strongly depended on the clinical profile of the patients involved. This raises the question whether it is possible to predict different training responses and better understand how this is determined by clinical characteristics, such as disease severity and the degree of cognitive impairment. Also, baseline task performance and early acquisition may determine long-term learning outcomes. Our main focus (primary dependent outcome) is to know which patients will be able to retain the learning gains after 4 weeks without training. For this aim, the investigators will use a home-based training program of a touchscreen task called the Swipe-Slide Pattern (SSP) task. Training of this SSP-task will be offered on a tablet under single and dual task conditions in a random fashion, not only to provide variation but also to increase the cognitive challenge, thereby stimulating consolidation. A crucial factor, which may affect the success of training, is compliance, which the investigators will measure objectively for the first time. As independent variables the investigators will measure several motor and cognitive functions as well as compliance, while including a broad sample of PD patients.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06738290
- Europe PMC full search
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06738290 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by KU Leuven
- Last refreshed: 3 March 2025
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06738290.
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