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NCT06737237: CERPICO
Cervical Plexus Versus Infiltration for Clavicular Operations (CERPICO)
NA trial testing cervical plexus block in Clavicle Surgery in 40 participants. Enrolling by invitation.
8 February 2028
Quick facts
| Lead sponsor | Naval Medical Center Camp Lejeune |
|---|---|
| Phase | NA |
| Status | ENROLLING BY INVITATION |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 40 |
| Start date | 8 May 2024 |
| Primary completion | 8 February 2028 |
| Estimated completion | 8 February 2028 |
| Sites | 1 location across United States |
Drugs / interventions tested
- cervical plexus block
- Local Infiltration Analgesia (LIA) — full drug profile →
- cervical plexus block
- Local Infiltration Analgesia (LIA) — full drug profile →
Conditions studied
- Clavicle Surgery — all drugs for Clavicle Surgery →
- Clavicle Fracture — all drugs for Clavicle Fracture →
- Acromioclavicular Joint — all drugs for Acromioclavicular Joint →
- Coracoclavicular Ligament — all drugs for Coracoclavicular Ligament →
Sponsor
Naval Medical Center Camp Lejeune
Who can join
Adults 18 to 64, any sex, with Clavicle Surgery or Clavicle Fracture. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Clavicle fractures are the most common fracture of the shoulder girdle, with young men being the most affected demographic. The incidence of clavicle fracture among military service members is 1.5-3x higher than the general adult population. While many clavicle fractures may be managed non-operatively, surgical intervention for clavicular fractures has shown improved functional outcomes in the active-duty Marine Corps population and an overall satisfactory return-to-duty rate. However, surgical fixation of the clavicle is associated with significant postoperative pain when no local anesthetic techniques are employed. Several regional anesthetic and local infiltrative analgesic regimens have been studied to improve postoperative pain control for clavicle ORIF with the authors concluding that intermediate cervical plexus block is the regional anesthesia therapy of choice for post-operative analgesia. A retrospective study by the same group determined that an intermediate cervical plexus block resulted in lower postoperative pain scores and opioid requirements than surgeon-administered local infiltration analgesia. This retrospective study unfortunately lacked participant blinding, randomization, a standardized anesthetic, consistent block technique, and protocolized postoperative analgesia. To date, no prospective trial has been performed directly comparing these two techniques. We propose, given the significance of clavicle fractures and corrective surgery in the military population, to study the efficacy of ultrasound-guided intermediate cervical plexus blocks as compared to local infiltration analgesia.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
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Related trials
Other trials of cervical plexus block
Trials testing the same drug.
- NCT05362162 — Comparison of Intermediate Cervical Plexus Block and Superficial Cervical Plexus Block · NA · completed
Other Naval Medical Center Camp Lejeune trials
Trials by the same sponsor.
- NCT05598723 — BOTOX® vs. XEOMIN® for Chronic Migraine · Phase 3 · recruiting
- NCT04260607 — Initiating Ketamine in Acutely Suicidal Patients in the Emergency Department · Phase 3 · terminated
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06737237 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Naval Medical Center Camp Lejeune
- Last refreshed: 16 April 2026
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