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NCT06735365
Comparative Effectiveness of Oxiris Hemofilters Versus Conventional Hemofilters in Septic Patients
trial testing CRRT in Sepsis - to Reduce Mortality in the Intensive Care Unit in 426 participants. Completed in 1 December 2024.
1 November 2024
Quick facts
| Lead sponsor | Bakirkoy Dr. Sadi Konuk Research and Training Hospital |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 426 |
| Start date | 23 May 2024 |
| Primary completion | 1 November 2024 |
| Estimated completion | 1 December 2024 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- CRRT
Conditions studied
- Sepsis - to Reduce Mortality in the Intensive Care Unit — all drugs for Sepsis - to Reduce Mortality in the Intensive Care Unit →
- Hemodiafiltration — all drugs for Hemodiafiltration →
- Cytokine — all drugs for Cytokine →
Sponsor
Bakirkoy Dr. Sadi Konuk Research and Training Hospital
Who can join
18 and older, any sex, with Sepsis - to Reduce Mortality in the Intensive Care Unit or Hemodiafiltration. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
We divided patients in 2 groups. First group was the patients who received Oxiris filters during CRRT. Second group was the patiens who have received CRRT filters other than Oxiris. We compared the lab parameters (Urea, Creatinin, Lactate, ABG parameters and SOFA escore with together.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Does oXiris Matter? A Comparative Outcome Study in Continuous Renal Replacement Therapy-Treated Septic Intensive Care Unit Patients.
Rahimi P, Tontu F, Khoundabi B, Soylu NB, et al · · 2026 · PMID 41248095 · DOI 10.1159/000549550
Verify or expand the search:
- PubMed search for NCT06735365
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
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Trials testing the same drug.
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Other recruiting trials for Sepsis - to Reduce Mortality in the Intensive Care Unit
Currently open trials in the same condition.
- NCT07179276 — Veno-arterial Carbon Dioxide Partial Pressure Difference (CO2gap) for Early Resuscitation of Septic Shock · NA · recruiting
- NCT06766461 — Beta-Lactam Antibiotics InitiaL ExpoSure OptimisEd in CriticallY Ill Patients with SEpsis · Phase 4 · recruiting
- NCT06891599 — ROTEM in Sepsis Trauma Outcome in Intensive Care · recruiting
Other Bakirkoy Dr. Sadi Konuk Research and Training Hospital trials
Trials by the same sponsor.
- NCT07425379 — Prehabilitation in Breast Cancer Surgery · NA · not yet recruiting
- NCT07367321 — Comparison of Onlay Mesh Repair and Sublay Mesh Repair in Umbilical Hernia Surgery · NA · not yet recruiting
- NCT07077629 — Geriatric Patients Undergoing Gynaecological Cancer Surgery · completed
- NCT07000461 — Transcranial Doppler as a Predictor of Postoperative Cognitive Dysfunction Following Cardiopulmonary Bypass · recruiting
- NCT07295405 — Water Temperature and Bowel Cleansing Quality · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06735365 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Bakirkoy Dr. Sadi Konuk Research and Training Hospital
- Last refreshed: 31 December 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06735365.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing