Last reviewed · How we verify
NCT06733714
Association of Transcranial Alternating Current Stimulation with Digital Cognitive Training for Cognitive Remediation in Older Adults
NA trial testing Transcranial Alternating Current Stimulation in Cognitive Dysfunction in 40 participants. Currently enrolling.
1 March 2027
Quick facts
| Lead sponsor | Universidade Federal do Rio de Janeiro |
|---|---|
| Phase | NA |
| Status | Recruiting now |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | triple |
| Primary purpose | treatment |
| Enrollment | 40 |
| Start date | 2 December 2024 |
| Primary completion | 1 March 2027 |
| Estimated completion | 1 March 2027 |
| Sites | 1 location across Brazil |
Drugs / interventions tested
- Transcranial Alternating Current Stimulation
- Digital Cognitive Training
Conditions studied
- Cognitive Dysfunction — all drugs for Cognitive Dysfunction →
- Alzheimer Disease — all drugs for Alzheimer Disease →
- Mild Cognitive Impairment — all drugs for Mild Cognitive Impairment →
- Cognitive Decline — all drugs for Cognitive Decline →
Sponsor
Universidade Federal do Rio de Janeiro — full company profile →
Who can join
50 and older, any sex, with Cognitive Dysfunction or Alzheimer Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
BACKGROUND Cognitive decline in older adults, especially those who develop Mild Cognitive Impairment and Alzheimer's Disease, currently has limited options of pharmacological treatments, with modest efficacy. Digital Cognitive Training (DCT) and Transcranial Alternating Current Stimulation (tACS) are two promising tools for cognitive remediation in this population. In this exploratory study, we investigate feasibility, tolerability and preliminary effects of the association of both interventions in older adults with cognitive complaints. METHODS Older adults with cognitive complaints are being enrolled for this study, which comprises 5 daily sessions of 30 minutes of DCT using the BrainHQ platform while simultaneously receiving theta tACS (6Hz, 1.6mA) targeting the Left Dorsolateral Prefrontal Cortex.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT06733714
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Transcranial Alternating Current Stimulation
Trials testing the same drug.
- NCT06873750 — Neuromodulation and FMRI in Neurodegenerative Diseases Study · NA · not yet recruiting
- NCT07323407 — Transcranial Alternating Current Stimulation for Refractory Constipation With Somatic Symptom Disorder · NA · recruiting
- NCT07045584 — Temporal Pole Transcranial Alternating Current Stimulation for Children With Autism Spectrum Disorder · NA · completed
- NCT06558890 — Transcranial Electrical Stimulation Targeting the Cerebellum for the Treatment of Refractory Temporal Lobe Epilepsy · NA · recruiting
- NCT05557786 — Treatment of Transcranial Alternating Current Stimulation（tACS）on Cerebellar Ataxia · NA · completed
Other recruiting trials for Cognitive Dysfunction
Currently open trials in the same condition.
- NCT07526740 — Brain Stimulation and Cognitive Training for MCI · NA · recruiting
- NCT07517237 — taVNS + CCT for Neurocognitive Rehab · NA · recruiting
- NCT07171450 — Cognitive Remediation · NA · recruiting
- NCT07418008 — The Liver Cirrhosis Cognitive Decline Scale (LiCCoS) · recruiting
- NCT07394504 — Effects of Turning Based Dual Task Training on Balance and Mild Cognitive Impairment in Diabetic Peripheral Neuropathy · NA · recruiting
Other Universidade Federal do Rio de Janeiro trials
Trials by the same sponsor.
- NCT07584564 — Application of the Concept of Proprioceptive Neuromuscular Facilitation in Trunk Control in Patients Admitted to the ICU · NA · not yet recruiting
- NCT07062497 — Clonidine in Ultrasound-guided Rectus Sheath Block for Outpatient Umbilical Hernioplasty · Phase 2, PHASE3 · recruiting
- NCT07191743 — Functional Assessment in Critically Ill Patients · recruiting
- NCT07391943 — Self-Guided CBT Mobile App for Treatment-Resistant Panic Disorder (CBT) Cognitive Behavioral Therapy · completed
- NCT06912451 — Sport Mouthguards: Devices for Preventing Dental Injuries in Sports · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06733714 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Universidade Federal do Rio de Janeiro
- Last refreshed: 13 December 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06733714.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing