Last reviewed · How we verify
NCT06730568
Effect of Different Non-surgical Treatment Approaches of Peri-implantitis
NA trial testing Submarginal mechanical instrumentation in Peri-implant Inflammation in 26 participants. Completed in 4 June 2018.
27 February 2018
Quick facts
| Lead sponsor | Yeditepe University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 26 |
| Start date | 27 November 2017 |
| Primary completion | 27 February 2018 |
| Estimated completion | 4 June 2018 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Submarginal mechanical instrumentation
- Submarginal mechanical instrumentation and chlorhexidine irrigation
- Submarginal mechanical instrumentation and ozone application
- Submarginal mechanical instrumentation and air abrasion
- Air abrasion monotherapy
Conditions studied
- Peri-implant Inflammation — all drugs for Peri-implant Inflammation →
- Peri-Implantitis and Peri-implant Mucositis — all drugs for Peri-Implantitis and Peri-implant Mucositis →
- Non-surgical Treatment — all drugs for Non-surgical Treatment →
Sponsor
Yeditepe University
Who can join
18 and older, any sex, with Peri-implant Inflammation or Peri-Implantitis and Peri-implant Mucositis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Peri-implantitis is a biofilm-associated pathological condition characterized by inflammation within the peri-implant mucosa, which leads to the progressive loss of the surrounding supporting bone tissue. The primary goal of managing peri-implantitis is to control the peri-implant biofilm and resolve inflammation. Nonsurgical treatment of peri-implantitis by submarginal mechanical instrumentation alone typically provides clinical improvements, particularly in non-advanced cases. However, to ensure surface decontamination and enhance treatment outcomes, alternative or adjunctive methods, such as systemic/local antibiotics, antiseptics, lasers, and air-abrasion systems, have been proposed. Therefore, the null hypothesis (H0) of the present study is that no statistically significant difference would be detected in clinical inflammation signs among patients diagnosed with early-stage peri-implantitis after undergoing one of the following treatments: nonsurgical mechanical instrumentation alone, mechanical instrumentation plus chlorhexidine (CHX), mechanical instrumentation plus gaseous ozone, mechanical instrumentation plus glycine air polishing, or glycine air polishing alone.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT06730568
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other Yeditepe University trials
Trials by the same sponsor.
- NCT07515833 — Loss of Balance Experienced by Industrial Workers Due to Hearing Problems · not yet recruiting
- NCT07477535 — Thoracic Mobility, Posture, Functional Capacity, and Respiratory Rate in Children Playing Wind Instruments · not yet recruiting
- NCT07495280 — Effects of Dynamic Neuromuscular Stabilization Exercises Versus Balance Exercises in Older Adults · NA · not yet recruiting
- NCT07521150 — Physiotherapy and Rehabilitation in Melorheostosis: A Case Report · NA · not yet recruiting
- NCT07325396 — Neuromuscular Training in Professional Esports Players · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06730568 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Yeditepe University
- Last refreshed: 12 December 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06730568.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing