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NCT06730165
Comparison of Transcutaneous Auricular Vagus and Trigeminal Nerve Stimulation
NA trial testing Transcutaneous Auricular Vagus Nerve Stimulation in Autonomic Nervous System Imbalance in 80 participants. Completed in 10 September 2024.
1 April 2024
Quick facts
| Lead sponsor | Bahçeşehir University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | single |
| Primary purpose | screening |
| Enrollment | 80 |
| Start date | 3 March 2024 |
| Primary completion | 1 April 2024 |
| Estimated completion | 10 September 2024 |
| Sites | 1 location across Turkey (Türkiye) |
Drugs / interventions tested
- Transcutaneous Auricular Vagus Nerve Stimulation
- Transcutaneous Auricular Trigeminal Nerve Stimulation
Conditions studied
- Autonomic Nervous System Imbalance — all drugs for Autonomic Nervous System Imbalance →
Sponsor
Bahçeşehir University
Who can join
Adults 20 to 50, any sex, with Autonomic Nervous System Imbalance. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of this study was to compare the results between transcutaneous auricular vagus nerve stimulation and trigeminal nerve stimulation with the results obtained from heart rate variability, pulse and blood pressure measurements and to reveal which method is more effective in autonomic nervous system neuromodulation. Hypotheses of the study: H0: Vagus nerve stimulation is more effective than trigeminal nerve simulation in terms of heart rate variability. H1: Trigeminal nerve stimulation is more effective than vagus nerve simulation in terms of heart rate variability.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Autonomic Effects of Transcutaneous Auricular Vagus and Trigeminal Nerve Stimulation: A Randomized, Sham-Controlled, and Single-Blind Study.
Perçin A, Özden AV, Yenişehir S, Albayrak HE. · · 2026 · PMID 41143755 · DOI 10.1016/j.neurom.2025.09.312
Verify or expand the search:
- PubMed search for NCT06730165
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Transcutaneous Auricular Vagus Nerve Stimulation
Trials testing the same drug.
- NCT07526415 — Effect of Recording Duration on Heart Rate Variability During taVNS · NA · not yet recruiting
- NCT07300774 — Vagus Nerve Stimulation in Premature Ejaculation · NA · not yet recruiting
- NCT06793800 — Effect of Transcutaneous Auricular Vagus Nerve Stimulation Application on Respiratory Functions in Stroke Patients · NA · recruiting
- NCT07000175 — Comparison of Heart Rate Variability Measurement on the Arm and Chest in Vagus Nerve Stimulation · NA · recruiting
- NCT06597149 — Effect of Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) on Plasma Insulin Levels · NA · recruiting
Other recruiting trials for Autonomic Nervous System Imbalance
Currently open trials in the same condition.
- NCT06359808 — Clinical Characteristics of Sleep Disorders in Patients With Ulcerative Colitis · recruiting
- NCT05212129 — Auricular Vagal Nerve Stimulation for Hypermobile Ehlers-Danlos Syndrome · NA · recruiting
Other Bahçeşehir University trials
Trials by the same sponsor.
- NCT07475819 — Posture Exercises and Ergonomics Education · NA · not yet recruiting
- NCT07453654 — Eye Exercises and Self-Cervical Mobilization in Office Workers With Neck Pain · NA · not yet recruiting
- NCT07471204 — Evaluation of Muscle Oxygenation and Recovery Dynamics in Individuals With Knee Osteoarthritis · recruiting
- NCT06749340 — Examining the Effects of Different Resistive Exercise Programs in Individuals With Compensated Liver Cirrhosis · NA · not yet recruiting
- NCT07367308 — External vs Combined Focus Effects on Landing in Female Athletes · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT06730165 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Bahçeşehir University
- Last refreshed: 12 December 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT06730165.
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